Journal of Anesthesia

, Volume 25, Issue 2, pp 286–290 | Cite as

Use of rocuronium–sugammadex, an alternative to succinylcholine, as a muscle relaxant during electroconvulsive therapy

  • Hiroko Hoshi
  • Yuji Kadoi
  • Jiro Kamiyama
  • Akiko Nishida
  • Hiroyuki Saito
  • Masaki Taguchi
  • Shigeru Saito
Clinical Report

Abstract

We compared the recovery time from neuromuscular blockade induced by rocuronium combined with sugammadex versus succinylcholine during electroconvulsive therapy (ECT). Anesthesia was induced using propofol, followed by succinylcholine (1 mg/kg) or rocuronium (0.6 mg/kg). Immediately after the seizure stopped, 16 mg/kg sugammadex was infused. Neuromuscular monitoring was performed and continued until recovery of the train-of-four ratio to 0.9. We compared the recovery time of T1 to 10 and 90% between groups. Patients were also assessed for clinical signs, such as time to first spontaneous breath from the administration of muscle relaxant and eye opening to verbal commands. Although recovery time of T1 to 10 and 90% in the rocuronium–sugammadex group was shorter than in the succinylcholine group, the difference was not statistically significant. Further, the seizure duration with succinylcholine (33 ± 8 s) was shorter than that with rocuronium–sugammadex (39 ± 4 s). In conclusion, this study demonstrates the potential benefit of use of rocuronium–sugammadex as an alternative to succinylcholine for muscle relaxation during ECT.

Keywords

Electroconvulsive therapy Muscle relaxant Rocuronium Sugammadex Succinylcholine 

Notes

Conflict of interest

None.

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Copyright information

© Japanese Society of Anesthesiologists 2011

Authors and Affiliations

  • Hiroko Hoshi
    • 1
  • Yuji Kadoi
    • 1
  • Jiro Kamiyama
    • 1
  • Akiko Nishida
    • 1
  • Hiroyuki Saito
    • 1
  • Masaki Taguchi
    • 1
  • Shigeru Saito
    • 1
  1. 1.Department of AnesthesiologyGunma University, School of MedicineMaebashiJapan

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