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Journal of Gastroenterology

, Volume 37, Issue 9, pp 709–716 | Cite as

Absence of specific symptoms in chronic hepatitis C

  • Motoki Iwasaki
  • Daisuke Kanda
  • Mitsuo Toyoda
  • Kazuhisa Yuasa
  • Yoshiaki Hashimoto
  • Hitoshi Takagi
  • Masatomo Mori
  • Shosuke Suzuki

Background:

No systematic research has been carried out on the symptoms of chronic hepatitis C, although the disease is believed to induce subjective symptoms such as fatigue or dullness in the legs. Methods: The Todai Health Index has been developed as a symptom checklist that is used for screening particular diseases or for health management. The index was chosen as the most suitable questionnaire for measuring characteristic symptoms of chronic hepatitis C. Sixty patients with chronic hepatitis C who did not have any severe complications were compared with healthy control subjects who were selected randomly from the residents of Isesaki City, Gunma, Japan. Results: The major findings were as follows: (1) male and female patients with chronic hepatitis C had no characteristic subjective physical symptoms when compared with the healthy controls, except for a significant difference in aggression, and (2) the severity of the hepatitis was not associated with the patients' symptoms after adjusting for age and treatments. Conclusions: Patients with chronic hepatitis C who did not have any severe complications did not show specific subjective physical symptoms.

Key words: hepatitis C virus cirrhosis Todai Health Index (THI) 

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Copyright information

© Springer-Verlag Tokyo 2002

Authors and Affiliations

  • Motoki Iwasaki
    • 1
  • Daisuke Kanda
    • 1
  • Mitsuo Toyoda
    • 1
  • Kazuhisa Yuasa
    • 1
  • Yoshiaki Hashimoto
    • 1
  • Hitoshi Takagi
    • 2
  • Masatomo Mori
    • 2
  • Shosuke Suzuki
    • 3
  1. 1. Isesaki Municipal Hospital, Isesaki, JapanJP
  2. 2. The First Department of Internal Medicine, Gunma University School of Medicine, Maebashi, JapanJP
  3. 3. Department of Public Health, Gunma University School of Medicine, 3 Showa, Maebashi 371-8511, JapanJP

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