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Journal of Gastroenterology

, Volume 52, Issue 7, pp 818–829 | Cite as

Different effects of dietary factors on reflux esophagitis and non-erosive reflux disease in 11,690 Korean subjects

  • Su Youn NamEmail author
  • Bum Joon Park
  • Yeong-Ah Cho
  • Kum Hei Ryu
  • Il Ju Choi
  • Sohee Park
  • Young-Woo Kim
Original Article—Alimentary Tract

Abstract

Background

Although dietary factors seem to be associated with gastroesophageal reflux symptoms, their effects on reflux esophagitis and non-erosive reflux disease (NERD) are unclear. We evaluate dietary effects on NERD and reflux esophagitis.

Methods

A total of 11,690 health check-up persons completed questionnaires for reflux symptoms and 3-day recordings for dietary intake and underwent esophagogastroduodenoscopy from 2004 to 2008. Multiple logistic regression with odds ratio (OR) and 95% confidence interval (CI) was used to evaluate the relationship of dietary components with NERD or reflux esophagitis.

Results

Prevalence of NERD and reflux esophagitis was 7.7 and 7.2%, respectively. In adjusted analysis, highest quartile of beans (OR 0.78, 95% CI 0.64–0.95), 3rd quartile of vegetables (OR 0.74, 95% CI 0.60–0.91), 4th quartile of fruit (OR 0.78, 95% CI 0.64–0.95), 4th quartile of egg (OR 0.78, 95% CI 0.64–0.96), and 3rd quartile of fish (OR 0.80, 95% CI 0.66–0.98), and 4th quartile of milk (OR 0.78, 95% CI 0.65–0.94) reduced NERD. Reflux esophagitis had no association with food groups, whereas it was related with men, absence of H. pylori, hiatal hernia, BMI, and total energy intake. Furthermore, dietary effect on NERD was similar in men and women, whereas highest tertile of potato (OR 1.91) and milk (OR 1.87) increased reflux esophagitis only in women.

Conclusions

While many food groups affected NERD, reflux esophagitis was associated with BMI and total energy intake rather than dietary component. These results may suggest different approaches toward dietary management of NERD and reflux esophagitis.

Keywords

Reflux esophagitis Non-erosive reflux disease Diet 

Notes

Acknowledgements

The authors thank Hyun Hee Kang, Kyoung A Ryu, and Min Kyong Yoo for acquiring the nutritional data.

Supplementary material

535_2016_1282_MOESM1_ESM.doc (57 kb)
Supplementary material 1 (DOC 57 kb)
535_2016_1282_MOESM2_ESM.docx (16 kb)
Supplementary material 2 (DOCX 16 kb)

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Copyright information

© Japanese Society of Gastroenterology 2016

Authors and Affiliations

  1. 1.Kyungpook National University Medical CenterKyungpook National University School of MedicineDaeguSouth Korea
  2. 2.Center for Cancer Prevention and DetectionNational Cancer CenterGoyangSouth Korea
  3. 3.Department of Clinical NutritionNational Cancer CenterGoyangSouth Korea
  4. 4.Center for Gastric CancerNational Cancer CenterGoyangSouth Korea
  5. 5.Cancer Biostatistics BranchNational Cancer CenterGoyangSouth Korea
  6. 6.Department of Biostatistics Graduate School of Public HealthYonsei UniversitySeoulSouth Korea

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