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Journal of Gastroenterology

, Volume 43, Issue 4, pp 251–255 | Cite as

Functional dyspepsia: past, present, and future

  • Brecht Geeraerts
  • Jan Tack
Review

Abstract

Functional dyspepsia (FD) is a highly prevalent gastrointestinal disorder characterized by symptoms originating from the gastroduodenal region in the absence of underlying organic disease that readily explains the symptoms. The Rome II consensus, which defined FD as the presence of unexplained pain or discomfort in the epigastrium, had a number of drawbacks, including an unjustified focus on pain, inclusion of a large number of nonspecific symptoms, and an unclear position on overlap with gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS). The Rome III consensus redefined FD as the presence of epigastric pain or burning, postprandial fullness or early satiation in the absence of underlying organic disease. Frequent overlap with GERD and IBS is acknowledged but does not exclude a diagnosis of FD. A subgroup classification into postprandial distress syndrome and epigastric pain syndrome was proposed. Ongoing studies will clarify the impact of this subdivision on clinical management and treatment outcomes.

Key words

Rome III consensus postprandial distress syndrome (PDS) epigastric pain syndrome (EPS) postprandial fullness early satiation 

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Copyright information

© Springer Japan 2008

Authors and Affiliations

  • Brecht Geeraerts
    • 1
  • Jan Tack
    • 1
  1. 1.Center for Gastroenterological Research K.U. LeuvenLeuvenBelgium

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