A pancreaticoduodenectomy is acceptable for periampullary tumors in the elderly, even in patients over 80 years of age
- 215 Downloads
Although the mortality rates for pancreaticoduodenectomy have been reported to be low for periampullary tumors at high-volume centers, postoperative results still remain unclear for elderly patients over 80 years of age.
This was a retrospective study of patients who underwent a pancreaticoduodenectomy and consisted of 335 patients who were treated for periampullary tumors between January 1994 and August 2008. The main outcomes were postoperative complications, mortality, and the length of hospital stay among the elderly patients, and they were analyzed in three groups: elderly patients over 80 years old, septuagenarians, and those under 70 years of age.
The performance status of elderly patients was lower than that of the patients under 70 (P < 0.05), and the elderly had a higher American Society of Anesthesiologists physical status classification score (P < 0.001) as well as low hemoglobin and serum albumin levels (P < 0.01 and P < 0.001, respectively). The incidence of delayed gastric emptying in the elderly was higher; however, there was no significant difference. The other outcomes in the elderly group were similar to those of the other groups.
Pancreaticoduodenectomy was considered to be a feasible surgical procedure for elderly patients who had a good performance status.
KeywordsPancreaticoduodenectomy Elderly Performance status Mortality Complication Delayed gastric emptying
- 1.Kincannon CL. National bibliography of US government publications. Statistial Abstract of the United States: 2004–2005. Washington: US Census Bureau; 2005.Google Scholar
- 2.Ishikawa A, Beppu M, Sato R. Population statistics of Japan 2006. Yamato-sogo. Tokyo, Japan; 2006.Google Scholar
- 4.Lillemoe KD. Pancreatic and periampullary carcinoma in the elderly. Gastrointestinal surgery in the elderly. Probl Gen Surg. 1996;13:108–20.Google Scholar
- 9.Bottger TC, Engelmann R, Junginger T. Is age a risk factor for major pancreatic surgery? An analysis of 300 resections. Hepatogastroenterol. 1999;46:2589–98.Google Scholar
- 26.Reid-Lombardo KM, Farnell MB, Crippa S, Barnett M, Maupin G, Bassi C, et al. Pancreatic anastomotic leakage after pancreaticoduodenectomy in 1,507 patients: a report from the pancreatic anastomotic leak study group. J Hepatobiliary Pancreat Surg. 2007;11:1451–9.Google Scholar