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Journal of Hepato-Biliary-Pancreatic Surgery

, Volume 15, Issue 2, pp 209–212 | Cite as

Renal cell carcinoma with unusual metastasis to the gallbladder

  • Hiroyuki Nojima
  • Akihiro Cho
  • Hiroshi Yamamoto
  • Matsuo Nagata
  • Nobuhiro Takiguchi
  • Osamu Kainuma
  • Hiroaki Souda
  • Hisashi Gunji
  • Akinari Miyazaki
  • Atsushi Ikeda
  • Ikuko Matsumoto
  • Takehide Asano
  • Munemasa Ryu
  • Naoki Nihei
  • Masayuki Maruoka
Case Reports of Interest

Abstract

Gallbladder involvement in patients with renal cell carcinoma (RCC) is extremely rare. We present a report of a 61-year-old man with a synchronous RCC metastasis to the gallbladder presenting as an intraluminal polypoid mass simulating primary gallbladder carcinoma. Enhanced abdominal computed tomography demonstrated a well-enhanced polypoid lesion in the gallbladder. Intraoperative rapid pathological examination of the gallbladder tumor showed clear cell-type cancerous cells. Microscopically, tumor cells of both the resected kidney and gallbladder had round uniform nuclei, clear cytoplasm, and well-defined cytoplasmic borders, forming alveolar patterns. Immunohistochemically, the tumor cells were negative for cytokeratin 7 (CK7) and carcinoembryonic antigen (CEA), which is usually positive in primary clear cell carcinoma of the gallbladder. Therefore, the final diagnosis was RCC with a synchronous gallbladder metastasis.

Key words

Renal cell carcinoma Gallbladder Metastasis 

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Copyright information

© Springer Japan 2008

Authors and Affiliations

  • Hiroyuki Nojima
    • 1
  • Akihiro Cho
    • 1
  • Hiroshi Yamamoto
    • 1
  • Matsuo Nagata
    • 1
  • Nobuhiro Takiguchi
    • 1
  • Osamu Kainuma
    • 1
  • Hiroaki Souda
    • 1
  • Hisashi Gunji
    • 1
  • Akinari Miyazaki
    • 1
  • Atsushi Ikeda
    • 1
  • Ikuko Matsumoto
    • 1
  • Takehide Asano
    • 1
  • Munemasa Ryu
    • 1
  • Naoki Nihei
    • 2
  • Masayuki Maruoka
    • 2
  1. 1.Department of Gastroenterological SurgeryChiba Cancer Center HospitalChibaJapan
  2. 2.Department of UrologyChiba Cancer Center HospitalChibaJapan

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