Oxaliplatin-desensitization procedure is safe and feasible in an outpatient cancer unit in France

  • Damien BotsenEmail author
  • Elise Lepoix
  • Camille Mazza
  • Mathilde Brasseur
  • Anne Grange
  • Florian Slimano
  • Olivier Bouché


This study was undertaken to assess the previously unevaluated safety and feasibility of oxaliplatin-desensitization procedure add a French ambulatory cancer unit, which is a current topic in oncology. Our findings demonstrated that oxaliplatin-desensitization was safe and feasible in our ambulatory cancer unit. In routine practice, all these procedures are done on an inpatient basis starting at least the day before. Those results could change oncological practices in France and improve patients’ quality of life and lower costs associated with inpatient administration.


Desensitization procedure Safety Ambulatory Anticancer drugs 



We acknowledge Janet Jacobson, an English-speaking American scientist, for her review of our clinical report.

Compliance with ethical standards

Research involving human participants and/or animals

For this type of study format consent is not required.

Informed consent

For this type of study format consent is not required.

Conflict of interest

Damien Botsen reports personal fees from Pierre Fabre and non-financial support from GlaxoSmithKline, Novartis, Chugai, and Amgen outside the submitted work.

Camille Mazza reports personal fees from Pierre Fabre outside the submitted work.

Mathilde Brasseur reports personal fees from Bayer and non-financial support from Pierre Fabre, Novartis, Amgen, Roche, and AbbVie outside the submitted work.

Olivier Bouche reports grants from Roche, personal fees from Roche, grants from Pierre Fabre, personal fees from Pierre Fabre, personal fees from Amgen, personal fees from Bayer, personal fees from Lilly, personal fees from Merck, personal fees from Novartis, outside the submitted work.

Elise Lepoix, Florian Slimano, and Anne Grange: none.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Ambulatory Cancer Unit, CHU ReimsRobert-Debré HospitalReims CedexFrance
  2. 2.Department of Gastroenterology and Digestive OncologyReims University HospitalReimsFrance
  3. 3.Department of Immunoallergy and Dermatology, CHU ReimsRobert-Debré HospitalReimsFrance
  4. 4.Department of Pharmacy, CHU ReimsRobert-Debré HospitalReimsFrance

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