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Effects of exercise on the quality of life in breast cancer patients: a systematic review of randomized controlled trials

  • Xinyan Zhang
  • Yuxiang Li
  • Dongling Liu
Review Article

Abstract

Purpose

The purpose of this study was to conduct a systematic review to assess the effect of exercise on the quality of life among people with breast cancer.

Methods

We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The Cochrane Library, PubMed, EMBASE, Web of Science, CINAHL, and four Chinese databases were searched for studies published until January 2018. The review included all randomized controlled trials that evaluated the effect of exercise on quality of life compared with that of usual care for people with breast cancer. Two reviewers independently assessed the quality of all the included studies using the Cochrane Handbook for Systematic Reviews of Interventions.

Results

In total, 36 studies (3914 participants) met the inclusion criteria. We divided the exercise into three modes: aerobic, resistance, and a combination of aerobic and resistance. All three modes of exercise intervention showed a significant effect on quality of life between groups.

Conclusions

Exercise is a safe and effective method of improving the quality of life in patients with breast cancer. In particular, combined training was associated with a significant improvement in quality of life. In future research, more high-quality, multicenter trials evaluating the effect of exercise in breast cancer patients are needed.

Keywords

Breast cancer Physical activity Quality of life Systematic review 

Abbreviations

BCS

Breast cancer subscale

BIRS

Body Image and Relationships Scale

EORTC QLQ-BR23

European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast

EORTC QLQ-C30

European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30

ES

Effect Size

FACT-A

Functional Assessment of Cancer Therapy-Anemia scale

FACT-B

Functional Assessment of Cancer Therapy-Breast questionnaire

FACT-G

Functional Assessment of Cancer Therapy-General

FWB

Functional well-being

HRQOL

Health-related quality of life

MCS

Mental health

PCS

Physical Component Summary

QOL

Quality of life

RCT

Randomized controlled trials

SF-36

36-item Short-Form Health Survey

TOI-An

Trial Outcome Index-Anemia

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.School of NursingJilin UniversityJilinPeople’s Republic of China

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