Gender-varying associations between physical activity intensity and mental quality of life in older cancer survivors
- 336 Downloads
Physical activity can enhance quality of life in cancer survivors, but this conclusion is based largely on research linking moderate-to-vigorous physical activity with quality of life. Light-intensity physical activity may be more feasible than more strenuous exercise for many older cancer survivors. This study reports a secondary analysis of baseline data from a lifestyle behavior intervention trial and examines the hypothesis that older cancer survivors who engage in more light-intensity physical activity, independent of moderate-to-vigorous activity, will report better mental quality of life.
Older (≥65 years), overweight or obese breast, prostate, or colorectal cancer survivors (n = 641, 54% female) self-reported their physical activity and mental quality of life (i.e., mental health, emotional role functioning, vitality, and social role functioning from the Short-Form 36 Health Status Survey) as a part of the RENEW trial baseline assessment. Analysis of covariance was used to test hypotheses.
For older women (but not men), light physical activity was positively associated with mental quality of life after adjusting for moderate-to-vigorous physical activity. Light physical activity that involved social participation appeared to be responsible for this association. For older men (but not women), moderate-to-vigorous physical activity was positively associated with mental quality of life.
Some activity appears to be better than none for important dimensions of mental quality of life. Experimental research is needed to test the hypothesis that older cancer survivors should strive to avoid inactivity regardless of whether they are able to engage in moderate-to-vigorous physical activity.
KeywordsCancer Oncology Walking Exercise Social participation Well-being
The authors thank the cancer survivors who so generously gave of their time to participate in the RENEW study, as well as Denise Snyder, MS, RD, and Richard Sloane, MPH.
This study was supported by the National Institutes of Health (R01 CA106919, P30AG028716) and the UAB Comprehensive Cancer Center.
Conflict of interest
The authors declare that they have no conflict of interest.
- 1.Hewitt M, Greenfield S, Stovall E (eds) (2005) From cancer patient to cancer survivor: lost in transition. National Academies Press, Washington, DCGoogle Scholar
- 2.Weaver KE, Forsythe LP, Reeve BB, Alfano CM, Rodriguez JL, Sabatino SA et al (2012) Mental and physical health-related quality of life among U.S. cancer survivors: population estimates from the 2010 National Health Interview Survey. Cancer Epidemiol Biomark Prev 21:2108–2117. doi: 10.1158/1055-9965.EPI-12-0740 CrossRefGoogle Scholar
- 6.Blair CK, Robien K, Inoue-Choi M, Rahn W, Lazovich D (2016) Physical inactivity and risk of poor quality of life among elderly cancer survivors compared to women without cancer: the Iowa Women’s Health Study. J Cancer Surviv res Pract 10:103–112. doi: 10.1007/s11764-015-0456-9 CrossRefGoogle Scholar
- 9.Thraen-Borowski KM, Trentham-Dietz A, Edwards DF, Koltyn KF, Colbert LH (2013) Dose-response relationships between physical activity, social participation, and health-related quality of life in colorectal cancer survivors. J Cancer Surviv res Pract 7:369–378. doi: 10.1007/s11764-013-0277-7 CrossRefGoogle Scholar
- 13.Physical Activity Guidelines Advisory Committee (2008) Physical activity guidelines advisory committee report, 2008. U.S. Department of Health and Human Services, Washington, DCGoogle Scholar
- 14.Courneya KS, Friedenreich CM, Quinney HA, Fields ALA, Jones LW, Vallance JKH et al (2005) A longitudinal study of exercise barriers in colorectal cancer survivors participating in a randomized controlled trial. Ann Behav med Publ Soc Behav med 29:147–153. doi: 10.1207/s15324796abm2902_9 CrossRefGoogle Scholar
- 23.Martin KR, Koster A, Murphy RA, Van Domelen DR, Hung M, Brychta RJ et al (2014) Changes in daily activity patterns with age in U.S. men and women: National Health and Nutrition Examination Survey 2003–04 and 2005–06. J am Geriatr Soc 62:1263–1271. doi: 10.1111/jgs.12893 CrossRefPubMedPubMedCentralGoogle Scholar
- 27.Morey MC, Snyder DC, Sloane R, Cohen HJ, Peterson B, Hartman TJ et al (2009) Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trial. Jama 301:1883–1891. doi: 10.1001/jama.2009.643 CrossRefPubMedPubMedCentralGoogle Scholar
- 28.Snyder DC, Morey MC, Sloane R, Stull V, Cohen HJ, Peterson B et al (2009) Reach out to ENhancE wellness in older cancer survivors (RENEW): design, methods and recruitment challenges of a home-based exercise and diet intervention to improve physical function among long-term survivors of breast, prostate, and colorectal cancer. Psychooncology 18:429–439. doi: 10.1002/pon.1491 CrossRefPubMedPubMedCentralGoogle Scholar
- 33.Ware JE, Kosinski M, Keller SK (1994) SF-36® physical and mental health summary scales: a user’s manual. The Health Institute, BostonGoogle Scholar
- 34.Ware JE, Snow KK, Kosinski M, Gandek B (1993) SF-36® health survey manual and interpretation guide. New England Medical Center, The Health Institute, BostonGoogle Scholar