Supportive Care in Cancer

, Volume 24, Issue 12, pp 4895–4899

Acupuncture for treating hot flashes in breast cancer patients: an updated meta-analysis

  • Alireza Salehi
  • Maryam Marzban
  • Abbas Rezian Zadeh
Original Article

DOI: 10.1007/s00520-016-3345-5

Cite this article as:
Salehi, A., Marzban, M. & Zadeh, A.R. Support Care Cancer (2016) 24: 4895. doi:10.1007/s00520-016-3345-5



The aim of this study was to evaluate the effectiveness of acupuncture for treatment of hot flash in women with breast cancer.


The aspects considered in this study included searching for 12 data bases until April 2015 and consulting reference lists of reviews and related articles. Additional features studied comprised all articles on human patients with breast cancer treated with needle acupuncture with or without electrical stimulation for the treatment of hot flashes. The methodological quality was assessed using the modified Jadad score.


The searches identified 12 relevant articles for inclusion. The meta-analysis without any subgroup or moderator failed to show favorable effects of acupuncture on reducing the frequency of hot flashes after intervention (n = 680, SMD = − 0.478, 95 % CI −0.397 to 0.241, P = 0.632) but exhibited marked heterogeneity of the results (Q value = 83.200, P = 0.000, I^2 = 83.17, τ^2 = 0.310).


The meta-analysis used had contradictory results and yielded no convincing evidence to suggest that acupuncture was an effective treatment of hot flash in patients with breast cancer. Multi-central studies including large sample size are required to investigate the efficiency of acupuncture for treating hot flash in patients with breast cancer.


Acupuncture Hot flash Breast cancer Systematic review and meta-analysis 

Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Alireza Salehi
    • 1
  • Maryam Marzban
    • 2
  • Abbas Rezian Zadeh
    • 3
  1. 1.Research Center for Traditional Medicine and History of MedicineShiraz University of Medical SciencesShirazIran
  2. 2.School of Health and Research Center for Health ScienceShiraz University of Medical ScienceShirazIran
  3. 3.Colorectal Research CenterShiraz University of Medical SciencesShirazIran

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