Fall-risk prediction in older adults with cancer: an unmet need
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Falls in older adults with cancer are more common than in noncancer controls, yet no fall-risk screening tool has been validated in this population. We undertook a cross-sectional pilot study of the Falls Risk Questionnaire (FRQ) in 21 adults aged ≥65 receiving systemic cancer therapy. Participants completed the FRQ, geriatric assessment measures, and a measure of fear-of-falling. The recruitment rate was 87.5 %, with 95.2 % completion of the FRQ and additional geriatric assessment and quality of life measures. The FRQ correlated significantly with the Timed Up and Go test (Pearson r 0.479, p = 0.028). In addition, the FRQ score correlated directly with fear-of-falling and inversely with QOL, particularly physical health and neurotoxicity subscales. In conclusion, the FRQ was feasible in older adults receiving cancer therapy and correlates with measures of physical performance, functional status, and fear-of-falling. The FRQ may prove to be a valuable fall-risk screening tool to implement fall-prevention interventions in this vulnerable population of older adults with cancer.
KeywordsCancer Aging Falls Geriatric assessment
This publication was made possible by Grant Number 1K12CA167540 through the National Cancer Institute (NCI) at the National Institutes of Health (NIH) and Grant Number UL1 TR000448 through the Clinical and Translational Science Award (CTSA) program of the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health. Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NCI, NCATS, or NIH.
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Conflict of interest
The authors declare that they have no conflict of interest.
- 9.Calhoun EA, Welshman EE, Chang C-H, Lurain JR, Fishman DA, Hunt TL et al (2003) Psychometric evaluation of the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (Fact/GOG-Ntx) questionnaire for patients receiving systemic chemotherapy. Int J Gynecol Cancer 13(6):741–748CrossRefPubMedGoogle Scholar
- 13.Hurria A, Mohile S, Gajra A, Klepin H, Muss H, Chapman A et al (2016) Validation of a prediction tool for chemotherapy toxicity in older adults with cancer. J Clin Oncol 16:1–9Google Scholar
- 19.Markle-Reid M, Browne G, Gafni A, Roberts J, Weir R, Thabane L et al (2010) The effects and costs of a multifactorial and interdisciplinary team approach to falls prevention for older home care clients “at risk” for falling: a randomized controlled trial. Can J Aging 29(1):139–161, Cambridge University PressCrossRefPubMedGoogle Scholar