Interventions for preparing patients for chemotherapy and radiotherapy: a systematic review
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Undergoing chemotherapy and radiotherapy can be physically and psychologically stressful for people with cancer. Providing preparatory information to cancer patients as they face treatment and its aftermath has the potential to improve patient outcomes. This study assessed the methodological quality and effectiveness of interventions providing preparatory information about chemotherapy and/or radiotherapy to cancer patients in improving patient outcomes and health care use.
MEDLINE, EMBASE, and Cochrane databases were systematically searched from January 1995 until October 2012. Inclusion criteria: (1) met Effective Practice and Organisation of Care (EPOC) criteria for study design; (2) included adults with a current cancer diagnosis; (3) delivered preparatory information via a health care provider or was self-directed; (4) examined psychological well-being, quality of life, physical symptoms, satisfaction, knowledge, or health service utilisation. Studies were assessed for methodological quality using the EPOC criteria.
Eighteen studies involving 3,443 cancer patients met inclusion criteria. Interventions included written information, audiotapes, videotapes, and computer programs. Interventions improved patient satisfaction (6/7 studies), information needs and patient knowledge (5/6 studies), physical symptoms (3/4 studies) and cost (1/1 study). More than half of the interventions improved psychological outcomes and quality of life (10/17 studies).
Providing preparatory information can improve patient-reported outcomes in cancer patients undergoing chemotherapy and radiotherapy, especially with respect to satisfaction and knowledge. Some, but not all, studies improved psychological outcomes and physical symptoms. There is a need for methodologically rigorous research to determine the most effective timing and method of delivery of preparatory information to improve patient outcomes.
KeywordsNeoplasm Chemotherapy Radiotherapy Patient education Preparatory information Systematic review
This research was supported by a Strategic Research Partnership Grant from Cancer Council NSW to the Newcastle Cancer Control Collaborative (New-3C), and infrastructure funding from the Hunter Medical Research Institute (HMRI). Dr. Jamie Bryant is supported by an Australian Research Council Post-Doctoral Industry Fellowship. Ms. Kristy Forshaw is supported by a University of Newcastle Postgraduate Research Scholarship.
Conflict of interest
The authors have declared no conflicts of interest. The authors have full control of all primary data and agree to allow the journal to review their data if requested.
- 18.National Health Service (2012) Cancer Patient Experience Survey 2011/12. NHS, LondonGoogle Scholar
- 19.Cancer Institute NSW (2009) New South Wales Cancer Patient Satisfaction Survey 2008. Cancer Institute NSW, SydneyGoogle Scholar
- 20.PHIDU (Public Health Information Development Unit) (2012) Messages from research: a review of the research literature concerning differences in cancer outcomes between metropolitan and country residents in South Australia, and factors that might underlie such differences. (Produced for Cancer Council SA). PHIDU, The University of Adelaide, AdelaideGoogle Scholar
- 21.Cancer Institute NSW, Evaluating the role of cancer care coordinator: summary report 2011, Cancer Institute NSW: Alexandria, NSWGoogle Scholar
- 30.National Breast Cancer Centre and National Cancer Control Initiative (2003) Clinical practice guidelines for the psychosocial care of adults with cancer. National Breast Cancer Centre, CamperdownGoogle Scholar
- 32.Higgins J et al (2011) Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (eds) Cochrane handbook for systematic reviews of interventions version 5.1.0 (updated March 2011). The Cochrane Collaboration. Available from www.cochrane-handbook.org
- 35.D’Haese S et al (2000) The effect of timing of the provision of information on anxiety and satisfaction of cancer patients receiving radiotherapy. J Cancer Educ 15(4):223–227Google Scholar
- 53.O’Brien L et al (2014) Education for cancer-related fatigue: could talking about it make people more likely to report it? Support Care Cancer 22(1):209–15Google Scholar