Supportive Care in Cancer

, Volume 22, Issue 7, pp 1857–1866

Complementary and alternative medicine use among patients with thoracic malignancies

  • Rashmi S. Bismark
  • Hongbin Chen
  • Grace K. Dy
  • Elizabeth A. Gage-Bouchard
  • Martin C. Mahoney
Original Article

Abstract

Purpose

Complementary and alternative medicine (CAM) use has been increasing among cancer patients. This study characterizes the use of CAM among patients with thoracic malignancies.

Methods

This cross sectional study was conducted at a National Cancer Institute-designated comprehensive cancer center among adult patients diagnosed with thoracic malignancies. The primary outcome was a self-reported use of CAM, defined as the use of any type of CAM beyond routine vitamin/mineral supplementation alone. A logistic regression model was developed to explore predictors of CAM use.

Results

A total of 108 patients completed a standardized survey (59 % response rate). Overall, 42 % of respondents reported the use of at least one type of CAM. Users and non-users of CAM did not differ based upon demographics, diagnosis, staging, smoking status, quality of life, or perceived understanding of cancer diagnosis. In the multivariate analysis, patients who reported feeling fearful about their future were four times more likely to be CAM users when compared to those who did not specify this emotion (odds ratio = 4.18; 95 % CI = 1.23–14.12; p = 0.02). Commonly cited reasons for CAM use were to support one’s self, boost immunity, and for improvements in emotional and/or spiritual well-being.

Conclusions

Prevalence of CAM use among cancer patients in this study was similar to the general US population. Feeling fearful about the future was associated with CAM use. Results suggest that patients may be turning to CAM as a therapeutic adjunct to actively cope with emotional distress surrounding the cancer experience.

Keywords

Lung neoplasms/complications/*therapy Complementary therapies/*utilization Cross-sectional studies 

References

  1. 1.
    WHO (2008) Cancer Fact Sheets. http://www.who.int/mediacentre/factsheets/fs297/en/. Accessed 21 Dec 2011
  2. 2.
    NCI (2011) SEER Stat Fact Sheets. http://seer.cancer.gov/statfacts/html/lungb.html. Accessed 25 March 2013
  3. 3.
    Siegel R, Naishadham D, Jemal A (2013) Cancer statistics, 2013. CA Cancer J Clin 63(1):11–30. doi:10.3322/caac.21166 PubMedCrossRefGoogle Scholar
  4. 4.
    Degner LF, Sloan JA (1995) Symptom distress in newly diagnosed ambulatory cancer patients and as a predictor of survival in lung cancer. J Pain Symptom Manag 10(6):423–431CrossRefGoogle Scholar
  5. 5.
    Graves KD, Arnold SM, Love CL, Kirsh KL, Moore PG, Passik SD (2007) Distress screening in a multidisciplinary lung cancer clinic: prevalence and predictors of clinically significant distress. Lung Cancer 55(2):215–224. doi:10.1016/j.lungcan.2006.10.001 PubMedCentralPubMedCrossRefGoogle Scholar
  6. 6.
    Correa-Velez I, Clavarino A, Eastwood H (2005) Surviving, relieving, repairing, and boosting up: reasons for using complementary/alternative medicine among patients with advanced cancer: a thematic analysis. J Palliat Med 8(5):953–961. doi:10.1089/jpm.2005.8.953 PubMedCrossRefGoogle Scholar
  7. 7.
    Kristoffersen AE, Fonnebo V, Norheim AJ (2009) Do cancer patients with a poor prognosis use complementary and alternative medicine more often than others? J Altern Complement Med 15(1):35–40. doi:10.1089/acm.2008.0262 PubMedCrossRefGoogle Scholar
  8. 8.
    NCCAM (2008) What is complementary and alternative medicine? [NCCAM CAM Basics]. http://nccam.nih.gov/health/whatiscam/. Accessed 21 Dec 2011
  9. 9.
    Deng GE, Frenkel M, Cohen L, Cassileth BR, Abrams DI, Capodice JL, Courneya KS, Dryden T, Hanser S, Kumar N, Labriola D, Wardell DW, Sagar S (2009) Evidence-based clinical practice guidelines for integrative oncology: complementary therapies and botanicals. J Soc Integr Oncol 7(3):85–120PubMedGoogle Scholar
  10. 10.
    Barnes PM, Bloom B, Nahin RL (2008) Complementary and alternative medicine use among adults and children: United States, 2007. National health statistics reports (12):1–23Google Scholar
  11. 11.
    Mao JJ, Palmer CS, Healy KE, Desai K, Amsterdam J (2011) Complementary and alternative medicine use among cancer survivors: a population-based study. J Cancer Surviv Res Pract 5(1):8–17. doi:10.1007/s11764-010-0153-7 CrossRefGoogle Scholar
  12. 12.
    Chrystal K, Allan S, Forgeson G, Isaacs R (2003) The use of complementary/alternative medicine by cancer patients in a New Zealand regional cancer treatment centre. N Z Med J 116(1168):U296PubMedGoogle Scholar
  13. 13.
    Ezeome ER, Anarado AN (2007) Use of complementary and alternative medicine by cancer patients at the University of Nigeria Teaching Hospital, Enugu, Nigeria. BMC Complement Alternat Med 7:28. doi:10.1186/1472-6882-7-28 CrossRefGoogle Scholar
  14. 14.
    Harris P, Finlay IG, Cook A, Thomas KJ, Hood K (2003) Complementary and alternative medicine use by patients with cancer in Wales: a cross sectional survey. Complement Ther Med 11(4):249–253PubMedCrossRefGoogle Scholar
  15. 15.
    Hyodo I, Amano N, Eguchi K, Narabayashi M, Imanishi J, Hirai M, Nakano T, Takashima S (2005) Nationwide survey on complementary and alternative medicine in cancer patients in Japan. J Clin Oncol Off J Am Soc Clin Oncol 23(12):2645–2654. doi:10.1200/JCO.2005.04.126 CrossRefGoogle Scholar
  16. 16.
    Pud D, Kaner E, Morag A, Ben-Ami S, Yaffe A (2005) Use of complementary and alternative medicine among cancer patients in Israel. Eur J Oncol Nurs: Off J Eur Oncol Nurs Soc 9(2):124–130. doi:10.1016/j.ejon.2005.03.011 CrossRefGoogle Scholar
  17. 17.
    Richardson MA, Sanders T, Palmer JL, Greisinger A, Singletary SE (2000) Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology. J Clin Oncol Off J Am Soc Clin Oncol 18(13):2505–2514Google Scholar
  18. 18.
    Boehmer L, Waqar S, Butler S, Sezhiyan A, Govindan R (2011) Summary of presentations from the 46th annual meeting of the American Society of Clinical Oncology (2010): focus on supportive care issues related to lung cancer. J Thorac Oncol: Off Publ Int Assoc Study Lung Cancer 6(3):645–649. doi:10.1097/JTO.0b013e318200f95d CrossRefGoogle Scholar
  19. 19.
    Deng GE, Rausch SM, Jones LW, Gulati A, Kumar NB, Greenlee H, Pietanza MC, Cassileth BR (2013) Complementary therapies and integrative medicine in lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143(5 Suppl):e420S–e436S. doi:10.1378/chest.12-2364 PubMedCrossRefGoogle Scholar
  20. 20.
    Molassiotis A, Panteli V, Patiraki E, Ozden G, Platin N, Madsen E, Browall M, Fernandez-Ortega P, Pud D, Margulies A (2006) Complementary and alternative medicine use in lung cancer patients in eight European countries. Complement Ther Clin Pract 12(1):34–39. doi:10.1016/j.ctcp.2005.09.007 PubMedCrossRefGoogle Scholar
  21. 21.
    Micke O, Buntzel J, Kisters K, Schafer U, Micke P, Mucke R (2010) Complementary and alternative medicine in lung cancer patients: a neglected phenomenon? Front Radiat Ther Oncol 42:198–205. doi:10.1159/000262477 PubMedCrossRefGoogle Scholar
  22. 22.
    Lovgren M, Wilde-Larsson B, Hok J, Levealahti H, Tishelman C (2011) Push or pull? Relationships between lung cancer patients’ perceptions of quality of care and use of complementary and alternative medicine. Eur J Oncol Nurs: Off J Eur Oncol Nurs Soc 15(4):311–317. doi:10.1016/j.ejon.2010.10.004 CrossRefGoogle Scholar
  23. 23.
    Wells M, Sarna L, Cooley ME, Brown JK, Chernecky C, Williams RD, Padilla G, Danao LL (2007) Use of complementary and alternative medicine therapies to control symptoms in women living with lung cancer. Cancer Nurs 30(1):45–55, quiz 56-47PubMedCrossRefGoogle Scholar
  24. 24.
    Mosher CE, Hanna N, Jalal SI, Fakiris AJ, Einhorn LH, Birdas TJ, Kesler KA, Champion VL (2013) Support service use and interest in support services among lung cancer patients. Lung Cancer 82(1):162–167. doi:10.1016/j.lungcan.2013.06.020 PubMedCrossRefGoogle Scholar
  25. 25.
    Naing A, Stephen SK, Frenkel M, Chandhasin C, Hong DS, Lei X, Falchook G, Wheler JJ, Fu S, Kurzrock R (2011) Prevalence of complementary medicine use in a phase 1 clinical trials program: the MD Anderson Cancer Center Experience. Cancer 117(22):5142–5150. doi:10.1002/cncr.26164 PubMedCrossRefGoogle Scholar
  26. 26.
    McCarty RL, Weber WJ, Loots B, Breuner CC, Vander Stoep A, Manhart L, Pihoker C (2010) Complementary and alternative medicine use and quality of life in pediatric diabetes. J Altern Complement Med 16(2):165–173. doi:10.1089/acm.2008.0566 PubMedCentralPubMedCrossRefGoogle Scholar
  27. 27.
    Dy GK, Bekele L, Hanson LJ, Furth A, Mandrekar S, Sloan JA, Adjei AA (2004) Complementary and alternative medicine use by patients enrolled onto phase I clinical trials. J Clin Oncol Off J Am Soc Clin Oncol 22(23):4810–4815. doi:10.1200/JCO.2004.03.121 CrossRefGoogle Scholar
  28. 28.
    Gansler T, Kaw C, Crammer C, Smith T (2008) A population-based study of prevalence of complementary methods use by cancer survivors: a report from the American Cancer Society’s studies of cancer survivors. Cancer 113(5):1048–1057. doi:10.1002/cncr.23659 PubMedCrossRefGoogle Scholar
  29. 29.
    Tindle HA, Davis RB, Phillips RS, Eisenberg DM (2005) Trends in use of complementary and alternative medicine by US adults: 1997–2002. Altern Ther Health Med 11(1):42–49PubMedGoogle Scholar
  30. 30.
    Davis EL, Oh B, Butow PN, Mullan BA, Clarke S (2012) Cancer patient disclosure and patient–doctor communication of complementary and alternative medicine use: a systematic review. Oncologist 17(11):1475–1481. doi:10.1634/theoncologist.2012-0223 PubMedCentralPubMedCrossRefGoogle Scholar
  31. 31.
    Buettner C, Kroenke CH, Phillips RS, Davis RB, Eisenberg DM, Holmes MD (2006) Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses’ health study. Breast Cancer Res Treat 100(2):219–227. doi:10.1007/s10549-006-9239-3 PubMedCrossRefGoogle Scholar
  32. 32.
    McDermott CL, Blough DK, Fedorenko CR, Arora NK, Zeliadt SB, Fairweather ME, Oakley-Girvan I, Van Den Eeden SK, Ramsey SD (2012) Complementary and alternative medicine use among newly diagnosed prostate cancer patients. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 20(1):65–73. doi:10.1007/s00520-010-1055-y CrossRefGoogle Scholar
  33. 33.
    Klafke N, Eliott JA, Wittert GA, Olver IN (2012) Prevalence and predictors of complementary and alternative medicine (CAM) use by men in Australian cancer outpatient services. Ann Oncol: Off J Eur Soc Med Oncol/ESMO 23(6):1571–1578. doi:10.1093/annonc/mdr521 CrossRefGoogle Scholar
  34. 34.
    Barnes PM, Powell-Griner E, McFann K, Nahin RL (2004) Complementary and alternative medicine use among adults: United States, 2002. Advance data (343):1–19Google Scholar
  35. 35.
    Hedderson MM, Patterson RE, Neuhouser ML, Schwartz SM, Bowen DJ, Standish LJ, Marshall LM (2004) Sex differences in motives for use of complementary and alternative medicine among cancer patients. Altern Ther Health Med 10(5):58–64PubMedGoogle Scholar
  36. 36.
    Kristoffersen AE, Norheim AJ, Fonnebo VM (2013) Complementary and alternative medicine use among Norwegian cancer survivors: gender-specific prevalence and associations for use. Evid Based Complement Alternat Med: eCAM 2013:318781. doi:10.1155/2013/318781 PubMedCentralPubMedCrossRefGoogle Scholar
  37. 37.
    Burstein HJ, Gelber S, Guadagnoli E, Weeks JC (1999) Use of alternative medicine by women with early-stage breast cancer. N Engl J Med 340(22):1733–1739. doi:10.1056/NEJM199906033402206 PubMedCrossRefGoogle Scholar
  38. 38.
    Stein KD, Kaw C, Crammer C, Gansler T (2009) The role of psychological functioning in the use of complementary and alternative methods among disease-free colorectal cancer survivors: a report from the American Cancer Society’s studies of cancer survivors. Cancer 115(18 Suppl):4397–4408. doi:10.1002/cncr.24591 PubMedCrossRefGoogle Scholar
  39. 39.
    Montazeri A, Sajadian A, Ebrahimi M, Haghighat S, Harirchi I (2007) Factors predicting the use of complementary and alternative therapies among cancer patients in Iran. Eur J Cancer Care 16(2):144–149. doi:10.1111/j.1365-2354.2006.00722.x CrossRefGoogle Scholar
  40. 40.
    Davidson R, Geoghegan L, McLaughlin L, Woodward R (2005) Psychological characteristics of cancer patients who use complementary therapies. Psycho-Oncology 14(3):187–195. doi:10.1002/pon.834 PubMedCrossRefGoogle Scholar
  41. 41.
    Hamilton AS, Miller MF, Arora NK, Bellizzi KM, Rowland JH (2012) Predictors of use of complementary and alternative medicine by non-Hodgkin lymphoma survivors and relationship to quality of life. Integr Cancer Ther. doi:10.1177/1534735412449733 PubMedGoogle Scholar
  42. 42.
    Henderson JW, Donatelle RJ (2003) The relationship between cancer locus of control and complementary and alternative medicine use by women diagnosed with breast cancer. Psycho-Oncology 12(1):59–67. doi:10.1002/pon.636 PubMedCrossRefGoogle Scholar
  43. 43.
    Sollner W, Maislinger S, DeVries A, Steixner E, Rumpold G, Lukas P (2000) Use of complementary and alternative medicine by cancer patients is not associated with perceived distress or poor compliance with standard treatment but with active coping behavior: a survey. Cancer 89(4):873–880PubMedCrossRefGoogle Scholar
  44. 44.
    Mao JJ, Palmer SC, Straton JB, Cronholm PF, Keddem S, Knott K, Bowman MA, Barg FK (2008) Cancer survivors with unmet needs were more likely to use complementary and alternative medicine. J Cancer Surviv Res Pract 2(2):116–124. doi:10.1007/s11764-008-0052-3 CrossRefGoogle Scholar
  45. 45.
    Elkins G, Fisher W, Johnson A (2010) Mind–body therapies in integrative oncology. Curr Treat Options in Oncol 11(3–4):128–140. doi:10.1007/s11864-010-0129-x CrossRefGoogle Scholar
  46. 46.
    Shennan C, Payne S, Fenlon D (2011) What is the evidence for the use of mindfulness-based interventions in cancer care? A review. Psycho-Oncology 20(7):681–697. doi:10.1002/pon.1819 PubMedCrossRefGoogle Scholar
  47. 47.
    Barton DL, Liu H, Dakhil SR, Linquist B, Sloan JA, Nichols CR, McGinn TW, Stella PJ, Seeger GR, Sood A, Loprinzi CL (2013) Wisconsin ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2. J Natl Cancer Inst 105(16):1230–1238. doi:10.1093/jnci/djt181 PubMedCrossRefGoogle Scholar
  48. 48.
    Balogh EP, Ganz PA, Murphy SB, Nass SJ, Ferrell BR, Stovall E (2011) Patient-centered cancer treatment planning: improving the quality of oncology care. Summary of an Institute of Medicine workshop. Oncologist 16(12):1800–1805. doi:10.1634/theoncologist.2011-0252 PubMedCentralPubMedCrossRefGoogle Scholar
  49. 49.
    Geffen JR (2010) Integrative oncology for the whole person: a multidimensional approach to cancer care. Integr Cancer Ther 9(1):105–121. doi:10.1177/1534735409355172 PubMedCrossRefGoogle Scholar
  50. 50.
    Maizes V, Rakel D, Niemiec C (2009) Integrative medicine and patient-centered care. Explore (NY) 5(5):277–289. doi:10.1016/j.explore.2009.06.008 CrossRefGoogle Scholar
  51. 51.
    Ernst E (2010) Complementary therapies for supportive cancer care. Support Care Cancer: Off J Multinatl Assoc Support Care Cancer 18(11):1365–1366. doi:10.1007/s00520-010-0991-x CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Rashmi S. Bismark
    • 1
    • 2
  • Hongbin Chen
    • 1
  • Grace K. Dy
    • 1
  • Elizabeth A. Gage-Bouchard
    • 2
  • Martin C. Mahoney
    • 1
    • 2
  1. 1.Roswell Park Cancer InstituteBuffaloUSA
  2. 2.SUNY University, School of Public Health and Health ProfessionsBuffaloUSA

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