How long do the effects of acupuncture on hot flashes persist in cancer patients?
- 574 Downloads
Acupuncture has been suggested as therapy for hot flashes in women with breast cancer and men with prostate cancer. In this systematic review, we sought to evaluate the long-term effects on vasomotor symptoms after the end of a defined treatment period of acupuncture in women with breast cancer and men with prostate cancer.
A literature search revealed 222 articles within the field. With defined exclusion criteria, we identified 17 studies. We also used the Jadad quality score and identified seven studies with a score of at least 3.
Six of seven identified studies qualified for inclusion in an analysis that measured frequency of hot flashes weighted in relation to number of patients (n = 172). The average reduction from baseline to end of acupuncture (ranging between 5 and 12 weeks of treatment) showed 43.2 % reduction of hot flashes. At the last follow-up (mean 5.8 months, range 3–9 months) after the end of therapy, the weighted reduction from baseline was sustained at 45.6 % in the 153 of 172 patients (89 %) who were followed up.
Data from six prospective analyzed studies indicate at least 3-month effects after the end of acupuncture treatment for flashes in women with breast cancer and men with prostate cancer. However, larger randomized trials with long-term follow-up will be needed to confirm these preliminary findings.
KeywordsAcupuncture Breast neoplasm Prostatic cancer Hot flashes
Conflict of interest
We declare no conflicts of interest. We have control of primary data regarding our own publications of original articles, but not primary data from other authors whose publications are included in this systematic review. We agree to allow the journal to review primary data regarding our own publications if requested.
- 5.Buchholz N-P, Mattarelli G, Huber Buchholz MM (1994) Post-orchiectomy hot flashes. Eur Urol 266:120–122Google Scholar
- 14.MacLennan AH, Broadbent JL, Lester S, et al. (2004) Oral oestrogen and combined oestrogen/progestagen therapy versus placebo for hot flashes. Cochrane Database Syst Rev (4):CD002978Google Scholar
- 26.Albertazzi P (2007) Non-estrogenic approaches for the treatment of climacteric symptoms. Climacteric 115–120. doi:10.1080/13697130701440980Google Scholar
- 35.Irani J, Salomon L, Oba R et al (2010) Efficacy of venlafaxine, medroxyprogesterone acetate, and cyproteroneactetate for the treatment of vasomotor hot flashes in men taking gonadotropin-releasing hormone analogues for prostate cancer: a double-blind, randomised trial. Lancet Oncol 11:147–154PubMedCrossRefGoogle Scholar