Supportive Care in Cancer

, Volume 21, Issue 9, pp 2387–2394 | Cite as

Factors associated with depressive symptoms in cancer family caregivers of patients receiving chemotherapy

  • Anna-leila Williams
  • Alison J. Holmes Tisch
  • Jane Dixon
  • Ruth McCorkle
Original Article

Keywords

Cancer family caregivers Depression Chemotherapy 

Notes

Acknowledgments

The parent study was supported by the National Institute of Health, National Center for Complementary and Alternative Medicine (F31AT003535; PI Williams). We greatly appreciate biostatistical support provided by Kristopher Fennie, Ph.D.

Conflict of interest

The authors do not have a financial relationship with the organization that sponsored the research. The authors have full control of all primary data and agree to allow Supportive Care in Cancer to review their data upon request.

References

  1. 1.
    National Alliance for Caregiving & AARP (2009) Caregiving in the U.S. National Alliance for Caregiving, WashingtonGoogle Scholar
  2. 2.
    Blum K, Sherman DW (2010) Understanding the experience of caregivers: a focus on transitions. Semin Oncol Nurs 26:243–258PubMedCrossRefGoogle Scholar
  3. 3.
    Deshields TL, Rihanek A, Potter P, Zhang Q, Kuhrik M, Kuhrik N, O’Neill J (2012) Psychosocial aspects of caregiving: perceptions of cancer patients and family caregivers. Support Care Cancer 20:349–356PubMedCrossRefGoogle Scholar
  4. 4.
    Given BA, Given CW, Kozachik S (2001) Family support in advanced cancer. CA Cancer J Clin 51:213–231PubMedCrossRefGoogle Scholar
  5. 5.
    Williams A, Mccorkle RM (2011) Cancer family caregivers during palliative, hospice, and bereavement phases: a review of the descriptive psychosocial literature. Palliat Support Care 9:315–325PubMedCrossRefGoogle Scholar
  6. 6.
    van Ryn M, Sanders S, Kahn K, van Houtven C, Griffin JM, Martin M, Atienza AA, Phelan S, Finstad D, Rowland J (2011) Objective burden, resources, and other stressors among informal caregivers: a hidden quality issue? Psychooncology 20:44–52PubMedCrossRefGoogle Scholar
  7. 7.
    McCorkle R, Siefert ML, Dowd MF et al (2007) Effects of advanced practice nursing on patient and spouse depressive symptoms, sexual function, and marital interaction after radical prostatectomy. Urol Nurs 27:65–77PubMedGoogle Scholar
  8. 8.
    Kurtz ME, Kurtz JC, Given CW, Given BA (2004) Depression and physical health among family caregivers of geriatric patients with cancer—a longitudinal view. Med Sci Monit 10:CR447–CR456PubMedGoogle Scholar
  9. 9.
    Carter P, Acton GJ (2006) Personality and coping: predictors of depression and sleep problems among caregivers of individuals who have cancer. J Gerontol Nurs 32:45–53PubMedGoogle Scholar
  10. 10.
    Fletcher BS, Paul SM, Dodd MJ, Schumacher K, West C, Cooper B, Lee K, Aouizerat B, Swift P, Wara W, Miaskowski CA (2009) Prevalence, severity, and impact of symptoms on female family caregivers of patients at the initiation of radiation therapy for prostate cancer. J Clin Oncol 26:599–605CrossRefGoogle Scholar
  11. 11.
    Mellon S, Northouse LL, Weiss LK (2006) A population-based study of the quality of life of cancer survivors and their family caregivers. Cancer Nurs 29:120–131PubMedCrossRefGoogle Scholar
  12. 12.
    Hodges LJ, Humphris GM, MacFarlane G (2005) A meta-analytic investigation of the relationship between the psychological distress of cancer patients and their carers. Soc Sci Med 60:1–12PubMedCrossRefGoogle Scholar
  13. 13.
    Grunfeld E, Coyle D, Whelan T, Clinch J, Reyno L, Earle CC, Willan A, Viola R, Coristine M, Janz T, Glossop R (2004) Family caregiver burden: results of a longitudinal study of breast cancer patients and their principal caregivers. CMAJ 170:1795–1801PubMedGoogle Scholar
  14. 14.
    Friethriksdottir N, Saevarsdottir T, Halfdanardottir SI, Jonsdottir A, Magnusdottir H, Olafsdottir KL, Guethmundsdottir G, Gunnarsdottir S (2011) Family members of cancer patients: needs, quality of life and symptoms of anxiety and depression. Acta Oncol 50:252–258PubMedCrossRefGoogle Scholar
  15. 15.
    Gaugler JE, Linder J, Given CW, Kataria R, Tucker G, Regine WF (2009) Family cancer caregiving and negative outcomes: the direct and mediational effects of psychosocial resources. J Fam Nurs 15:417–444PubMedCrossRefGoogle Scholar
  16. 16.
    Mystakidou K, Tsilika E, Parpa E, Galanos A, Vlahos L (2007) Caregivers of advanced cancer patients: feelings of hopelessness and depression. Cancer Nurs 30:412–418PubMedCrossRefGoogle Scholar
  17. 17.
    Palos GR, Mendoza TR, Liao KP, Anderson KO, Garcia-Gonzalez A, Hahn K, Nazario A, Ramondetta LM, Valero V, Lynch GR, Jibaja-Weiss ML, Cleeland CS (2007) Caregiver symptom burden: the risk of caring for an underserved patient with advanced cancer. Cancer 117:1070–1079CrossRefGoogle Scholar
  18. 18.
    Rhee YS, Yun YH, Park S, Shin DO, Lee KM, Yoo HJ, Kim JH, Kim SO, Lee R, Lee YO, Kim NS (2008) Depression in family caregivers of cancer patients: the feeling of burden as a predictor of depression. J Clin Oncol 26:5890–5895PubMedCrossRefGoogle Scholar
  19. 19.
    Schumacher KL, Stewart BJ, Archbold PG, Caparro M, Mutale F, Agrawal S (2008) Effects of caregiving demand, mutuality, and preparedness on family caregiver outcomes during cancer treatment. Oncol Nurs Forum 35:49–56PubMedCrossRefGoogle Scholar
  20. 20.
    Siminoff LA, Wilson-Genderson M, Baker S (2010) Depressive symptoms in lung cancer patients and their family caregivers and the influence of family environment. Psychooncology 19:1285–1293PubMedCrossRefGoogle Scholar
  21. 21.
    Hewitt M, Greenfield S, Stovall E (2006) Improving care and quality of life. In: Hewitt M, Ganz P (eds) From cancer patient to cancer survivor: lost in transition: society of clinical oncology and institute of medicine symposium. National Academies Press, WashingtonGoogle Scholar
  22. 22.
    DuBenske LL, Wen KY, Gustafson DH, Guarnaccia CA, Cleary JF, Dinauer SK, McTavish FM (2008) Caregivers’ differing needs across key experiences of the advanced cancer disease trajectory. Palliat Support Care 6:265–272PubMedCrossRefGoogle Scholar
  23. 23.
    Squiers L, Finney Rutten LJ, Treiman K, Bright MA, Hesse B (2005) Cancer patients’ information needs across the cancer care continuum: evidence from the cancer information service. J Health Commun 10(Suppl 1):15–34PubMedCrossRefGoogle Scholar
  24. 24.
    Williams A, Dixon J, Van Ness P, McCorkle R (2011) Determinants of meditation practice inventory: development, content validation, and initial psychometric testing. Altern Ther Health Med 17:16–23PubMedGoogle Scholar
  25. 25.
    Williams A, Van Ness P, Dixon J, McCorkle R (2012) Differences in barriers to meditation by gender and age among cancer family caregivers. Nurs Res 61:22–27PubMedCrossRefGoogle Scholar
  26. 26.
    Radloff LS (1977) The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1:385–401CrossRefGoogle Scholar
  27. 27.
    Given CW, Given B, Stommel M, Collins C, King S, Franklin S (1992) The caregiver reaction assessment for caregivers to persons with chronic physical and mental impairments. Res Nurs Health 15:271–283PubMedCrossRefGoogle Scholar
  28. 28.
    John O, Naumann L, Soto C (2008) Paradigm shift to the integrative Big Five trait taxonomy. In: John OP, Robins RW, Pervin LA (eds) Handbook of personality: theory and research, 3rd edn. Guilford, New York, pp 114–158Google Scholar
  29. 29.
    Sherwood PR, Given BA, Donovan H, Baum A, Given CW, Bender CM, Schulz R (2008) Guiding research in family care: a new approach to oncology caregiving. Psychooncology 17:986–996PubMedCrossRefGoogle Scholar
  30. 30.
    Stommel M, Wang S, Given C, Given B (1992) Focus on psychometrics: confirmatory factor analysis as a method to assess measurement equivalence. Res Nurs Heal 15:399–405CrossRefGoogle Scholar
  31. 31.
    Kurtz ME, Kurtz JC, Given CW, Given BA (2005) Randomized, controlled trial of a patient/caregiver symptom control intervention: effects on depressive symptomatology of caregivers of cancer patients. J Pain Symptom Manag 30:112–122CrossRefGoogle Scholar
  32. 32.
    Stetz KM, Brown M (2004) Physical and psychosocial health in family caregiving: a comparison of AIDS and cancer caregivers. Public Health Nurs 21:533–540PubMedCrossRefGoogle Scholar
  33. 33.
    National Institutes of Health (2001) NIH policy on reporting race and ethnicity data: subjects in clinical research. http://grants.nih.gov/grants/guide/notice-files/NOT-OD-01-053.html. Accessed 16 Mar 2013
  34. 34.
    Swore Fletcher BA, Dodd MJ, Schumacher KL, Miaskowski C (2008) Symptom experience of family caregivers of patients with cancer. Oncol Nurs Forum 35:E23–E44PubMedCrossRefGoogle Scholar
  35. 35.
    Given B, Given CW, Sikorskii A, Jeon S, Sherwood P, Rahbar M (2006) The impact of providing symptom management assistance on caregiver reaction: results of a randomized trial. J Pain Symptom Manag 32:433–443CrossRefGoogle Scholar
  36. 36.
    Francis LE, Bowman KF, Kypriotakis G, Rose JH (2011) Relationships and emotional wellbeing among African American and white advanced cancer caregivers. Patient Educ Couns 85:446–453PubMedCrossRefGoogle Scholar
  37. 37.
    Kim Y, Baker F, Spillers RL, Wellisch DK (2006) Psychological adjustment of cancer caregivers with multiple roles. Psychooncology 15:795–804PubMedCrossRefGoogle Scholar
  38. 38.
    Dumont S, Turgeon J, Allard P, Gagnon P, Charbonneau C, Vezina L (2006) Caring for a loved one with advanced cancer: determinants of psychological distress in family caregivers. J Palliat Med 9:912–921PubMedCrossRefGoogle Scholar
  39. 39.
    Siefert ML, Williams AL, Dowd MF, Chappel-Aiken L, McCorkle R (2008) The caregiving experience in a racially diverse sample of cancer family caregivers. Cancer Nurs 31:399–407PubMedCrossRefGoogle Scholar
  40. 40.
    Iconomou G, Viha A, Kalofonos HP, Kardamakis D (2001) Impact of cancer on primary caregivers of patients receiving radiation therapy. Acta Oncol 40:766–771PubMedCrossRefGoogle Scholar
  41. 41.
    Pinquart M, Sorensen S (2007) Correlates of physical health of informal caregivers: a meta-analysis. J Gerontol B Psychol Sci Soc Sci 62:126–137CrossRefGoogle Scholar
  42. 42.
    Cameron JI, Franche RL, Cheung AM, Stewart DE (2002) Lifestyle interference and emotional distress in family caregivers of advanced cancer patients. Cancer 94:521–527PubMedCrossRefGoogle Scholar
  43. 43.
    Sharpe L, Butow P, Smith C, McConnell D, Clarke S (2005) The relationship between available support, unmet needs and caregiver burden in patients with advanced cancer and their carers. Psychooncology 14:102–114PubMedCrossRefGoogle Scholar
  44. 44.
    Lorant V, Deliege D, Eaton W, Robert A, Philippot P, Ansseau M (2003) Socioeconomic inequalities in depression: a meta-analysis. Am J Epidemiol 157:98–112PubMedCrossRefGoogle Scholar
  45. 45.
    Northouse L, Williams AL, Given B, McCorkle R (2012) Psychosocial care for family caregivers of patients with cancer. J Clin Oncol 30:1227–1234PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Anna-leila Williams
    • 1
  • Alison J. Holmes Tisch
    • 2
  • Jane Dixon
    • 2
  • Ruth McCorkle
    • 2
  1. 1.Frank H. Netter MD School of MedicineQuinnipiac UniversityHamdenUSA
  2. 2.School of NursingYale UniversityNew HavenUSA

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