Supportive Care in Cancer

, Volume 20, Issue 11, pp 2697–2704 | Cite as

Functional status and health-related quality of life among allogeneic transplant patients at hospital discharge: a comparison of sociodemographic, disease, and treatment characteristics

  • Marcia Grant
  • Liz Cooke
  • Anna Cathy Williams
  • Smita Bhatia
  • Leslie Popplewell
  • Gwen Uman
  • Stephen Forman
Original Article



The purpose of this paper is to report the findings of a study of hematopoietic cell transplant patients, describing the needs of allogeneic transplant patients at the time of discharge in regard to their functional status, quality of life (QOL), and caregiver information and comparing these needs across a number of sociodemographic, disease, and treatment characteristics. The findings of this study are part of a larger mixed-methods study, representing one data time point of the larger study.


This paper will discuss the baseline data collected at the time of discharge for 282 allogeneic transplant patients, which include sociodemographic data combined with disease, treatment, functional status, and QOL data to present a comprehensive portrait of the transplant patient at discharge.


Mean age was 48 years, males represented 52%, and 22% of the patients were Hispanic. The majority of the patients had acute leukemia (55%), were diagnosed within the last 3 years, and had matched unrelated (52%) transplants. The time from transplant to discharge averaged 30 days. Mean scores for QOL (scale = 1–10, with 10 = best QOL) included a low score of 5.7 for both psychological and social well-being, 6.3 for overall QOL, and 7.1 for both physical and spiritual well-being. Males had significantly higher QOL than females, as did non-Hispanics. Patients with Hodgkin’s disease had significantly lower overall QOL scores.


Our results highlight the physical, psychological, social, and spiritual challenges which present for patients and their caregivers at the time of hospital discharge following allogeneic transplant.


Allogeneic transplant Discharge status Quality of life 



This study was supported by the NCI R01-CA107446, Standardized Nursing Intervention Protocol for HCT Patients.

Conflict of interest

The authors do not have financial relationship with the organization that sponsored the research. We have full control of all primary data and agree to allow the journal to review the data if requested.


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Marcia Grant
    • 1
  • Liz Cooke
    • 1
  • Anna Cathy Williams
    • 1
  • Smita Bhatia
    • 2
  • Leslie Popplewell
    • 3
  • Gwen Uman
    • 4
  • Stephen Forman
    • 3
  1. 1.Division of Nursing Research and EducationCity of HopeDuarteUSA
  2. 2.Division of Outcomes ResearchCity of HopeDuarteUSA
  3. 3.Division of HematologyCity of HopeDuarteUSA
  4. 4.Vital Research LLCLos AngelesUSA

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