Supportive Care in Cancer

, Volume 19, Issue 9, pp 1357–1365

Quality of life concerns and depression among hematopoietic stem cell transplant survivors

  • Catherine E. Mosher
  • Katherine N. DuHamel
  • Christine Rini
  • Geoffrey Corner
  • Joanne Lam
  • William H. Redd
Original Article

DOI: 10.1007/s00520-010-0958-y

Cite this article as:
Mosher, C.E., DuHamel, K.N., Rini, C. et al. Support Care Cancer (2011) 19: 1357. doi:10.1007/s00520-010-0958-y

Abstract

Purpose

This study examined quality of life, transplant-related concerns, and depressive symptoms and their demographic and medical correlates at 1 to 3 years following hematopoietic stem cell transplantation (HSCT).

Methods

HSCT survivors (N = 406) completed telephone-administered questionnaires that assessed demographic variables, functional status, quality of life, transplant-related concerns, and depressive symptoms.

Results

The most prevalent concerns among HSCT survivors included physical symptoms (e.g., fatigue and pain), maintaining current health status and employment, changes in appearance, and lack of sexual interest and satisfaction. In addition, almost one-third (32%) of survivors age 40 years and younger reported concern about their ability to have children. Unemployed survivors and those with lower incomes and worse functional status were more likely to experience poorer quality of life in multiple domains. Fifteen percent of the sample reported moderate to severe depressive symptoms, and these symptoms were higher among allogeneic transplant recipients and those with lower functional status.

Conclusions

Results suggest that interventions are needed to address physical symptoms, coping with an uncertain future, infertility, and sexual issues during the early phase of HSCT survivorship.

Keywords

Hematopoietic stem cell transplantation Quality of life Cancer survivorship Psychological Depression Sexual health 

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Catherine E. Mosher
    • 1
  • Katherine N. DuHamel
    • 1
  • Christine Rini
    • 2
  • Geoffrey Corner
    • 1
  • Joanne Lam
    • 1
  • William H. Redd
    • 2
  1. 1.Department of Psychiatry and Behavioral SciencesMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Department of Oncological SciencesThe Mount Sinai School of MedicineNew YorkUSA

Personalised recommendations