Supportive Care in Cancer

, Volume 17, Issue 4, pp 437–444 | Cite as

Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

  • N. KearneyEmail author
  • L. McCann
  • J. Norrie
  • L. Taylor
  • P. Gray
  • M. McGee-Lennon
  • M. Sage
  • M. Miller
  • R. Maguire
Original Article



To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.


A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.


Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.


One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.


A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©).

Main outcome measures

Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea).


There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand–foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).


The study demonstrates that ASyMS© can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.


Chemotherapy Symptoms Technology Assessment 



The authors would like to thank Stirling University Research Enterprise for funding this study and would like to extend a special thank you and note of appreciation to all the patients and health professionals who participated.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • N. Kearney
    • 1
    Email author
  • L. McCann
    • 1
  • J. Norrie
    • 2
  • L. Taylor
    • 1
  • P. Gray
    • 3
  • M. McGee-Lennon
    • 3
  • M. Sage
    • 4
  • M. Miller
    • 1
  • R. Maguire
    • 1
  1. 1.Cancer Care Research Centre, Department of Nursing and MidwiferyUniversity of StirlingStirlingUK
  2. 2.Centre for Healthcare Randomised Trials, Health Services Research UnitUniversity of AberdeenAberdeenUK
  3. 3.Department of Computing ScienceUniversity of GlasgowGlasgowUK
  4. 4.Kelvin Connect LtdHillington Park Innovation CentreGlasgowUK

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