Supportive Care in Cancer

, Volume 16, Issue 3, pp 261–266 | Cite as

The relationship between insomnia and patient satisfaction with quality of life in cancer

  • Christopher G. Lis
  • Digant Gupta
  • James F. Grutsch
Original Article


Goals of work

Insomnia is the most common sleep disorder in patients with advanced cancer. The goal of this study was to investigate the relationship between insomnia and patient satisfaction with quality of life (QoL) in cancer.

Materials and methods

A case series of 954 cancer patients treated at Cancer Treatment Centers of America was investigated. Insomnia was measured using the EORTC QLQ-C30 insomnia subscale. Patient satisfaction with QoL was measured using the Ferrans and Powers Quality of Life Index (QLI). The relationship between insomnia and QLI was evaluated using multivariate analysis of variance and multiple regression analysis.


Of 954 patients, 579 were females and 375 males, with the median age at presentation of 56 years (range, 20–90 years). Most common cancers were breast (26%), colorectal (19%), and lung (16%). After controlling for the effects of age and treatment history, every 10-unit increase in insomnia was statistically significantly associated with 0.67-, 0.17-, 0.42-, 0.20-, and 0.42-unit decline in QLI health/physical, social/economic, psychological/spiritual, family, and overall QoL functioning, respectively.


We found that insomnia is strongly correlated with patient satisfaction with QoL in cancer. Future studies should evaluate the impact of integrative cancer care services on patient satisfaction with QoL.


Insomnia Quality of life Cancer Supportive care Patient satisfaction 



This study was funded by Cancer Treatment Centers of America. We thank Thom Wodek, Tanya Jordan, and Jody Wehrwein, our clinical research coordinators, for their contributions in the administration of quality of life questionnaires to our patients and subsequent data entry.


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Christopher G. Lis
    • 1
  • Digant Gupta
    • 1
  • James F. Grutsch
    • 1
  1. 1.Office of ResearchCancer Treatment Centers of America® (CTCA), Midwestern Regional Medical CenterZionUSA

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