Evaluation of a 12-week home-based walking intervention for breast cancer survivors
- 1.4k Downloads
Goals of work
To evaluate a 12-week home-based walking intervention among breast cancer survivors and to quantify changes in physical activity (PA) behaviors, body weight, and body composition in response to the intervention.
Patients and methods
Breast cancer survivors that were in the posttreatment period were randomized to intervention (n=23) or wait-list usual care (n=13). PA was assessed by self-report, and in a study subsample (n=23), by an accelerometer. Intention to treat principles were employed to estimate the intervention effect on PA behaviors, body weight, and body composition. Intervention adherence was calculated as the proportion of exercise sessions completed relative to the number of exercise sessions recommended, as reported each week on walking logs.
Thirty-four of 36 women randomized (94%) completed the study. Average intervention adherence over 12 weeks was 94%. Intervention participants reported a significantly greater increase in walking for exercise [+11.9 metabolic equivalent (MET)-h/week] over time than did usual care participants (+1.7 MET-h/week, p=0.01). Objective measures of activity also indicated that intervention participants increased their activity levels over time as compared to usual care participants [i.e., counts/min/day and steps/day (p≤0.04)]. No significant changes in body weight or composition were observed.
We found that a 12-week home-based walking intervention was safe and effective for increasing short-term PA levels in breast cancer survivors. Future studies are needed to assess the ability of brief interventions to facilitate the maintenance of increased activity levels and to produce favorable quality of life and risk factor outcomes.
KeywordsExercise Physical activity Behavior change Accelerometer
We would like to thank Ms. Amy Skiba, M.S., for her dedicated efforts on behalf or the Breast Cancer Walking Study. This research was supported financially by the Vanderbilt-Ingram Cancer Center, the South Carolina Cancer Center, and the Vanderbilt General Clinical Research Center (M01 RR-00095).
- 1.ACSM (2004) ACSM position stand on the appropriate intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports 33:2145–2156Google Scholar
- 2.American Cancer Society (2005) Cancer facts and figures—2005. American Cancer Society, Atlanta, GAGoogle Scholar
- 3.Byers T, Nestle M, McTiernan A, Doyle C, Currie-Williams A, Gansler T, Thun M (2002) American cancer society guidelines on nutrition and physical activity for cancer prevention: reducing the risk for cancer with healthy food choices and physical activity. CA Cancer J Clin 52:92–119PubMedCrossRefGoogle Scholar
- 12.Fairey AS, Courneya KS, Field CJ, Bell GJ, Jones LW, Mackey JR (2003) Effects of exercise training on fasting insulin, insulin resistance, insulin-like growth factors, and insulin-like growth factor binding proteins in postmenopausal breast cancer survivors: a randomized controlled trial. Cancer Epidemiol Biomark Prev 12:721–727Google Scholar
- 13.Frison L, Pocock SJ (2005) Repeated measures in clinical trials: analysis using mean summary statistics and its implications for design. Stat Med 11:1685–1704Google Scholar
- 20.Littell R, Milliken G, Stroup W, Wolfinger R (1996) SAS system for mixed models. SAS, Cary, NC, p 633Google Scholar
- 22.McTiernan A, Ulrich C, Kumai C, Bean D, Schwartz R, Mahloch J, Hastings R, Gralow J, Potter JD (1998) Anthropometric and hormone effects of an eight-week exercise-diet intervention in breast cancer patients: results of a pilot study. Cancer Epidemiol Biomark Prev 7:477–481Google Scholar