Supportive Care in Cancer

, Volume 14, Issue 2, pp 109–115 | Cite as

Oxymorphone: a review

  • Eric PrommerEmail author
Review Article


Oxymorphone (oxymorphone hydrochloride) (14-hydroxy-dihydromorphinone), a semisynthetic μ-opioid agonist, was first approved by the US Food and Drug Administration in 1959. Oxymorphone is considered a more potent opioid than its parent compound, morphine. Recently, an immediate-release and long-acting oral formulation of this drug was developed that makes oxymorphone a new option in treating moderate to severe pain. This article reviews the pharmacodynamics, pharmacology, and clinical efficacy for this new option in treating moderate to severe pain.


Oxymorphone Opioid receptors Opioid Pharmacokinetics 


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.VIP Palliative Care Program Greater Los Angeles Healthcare, Division of Hematology/OncologyUCLA School of MedicineLos AngelesUSA

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