Wiener klinische Wochenschrift

, Volume 127, Issue 17–18, pp 707–714 | Cite as

Clinical-Pathological Conference Series from the Medical University of Graz Case No 155: 26-year-old woman in third trimester of pregnancy with epigastric pain and thrombocytopenia

  • Elisabeth Fabian
  • Florian Eisner
  • Ingrid Pabinger
  • Christian Viertler
  • Sigrid Regauer
  • Andreas Lueger
  • Peter Neumeister
  • Eva-Christine Weiss
  • Wolfgang Schöll
  • Uwe Lang
  • Florian Prüller
  • Guenter J. KrejsEmail author
Clinical-Pathological Conference

Presentation of case

Dr. F. Eisner

Due to epigastric pain, the unemployed pregnant woman had been examined at the outpatient clinic of the Styrian Public Health Service 2 months earlier. At that time, all laboratory tests were reportedly within normal limits and the epigastric pain was said not to be unusual during pregnancy. However, when the symptoms became more severe, she presented at the Obstetrics Outpatient Clinic at the University Medical Center in Graz, where thrombocytopenia with a platelet count of 9 G/l (normal: 140–440 G/l) was diagnosed. Other laboratory test results were: leukocytes 15.6 G/l (normal: 4.4–11.3 G/l), erythrocytes 2.4 T/l (normal: 4.1–5.1 T/l), hemoglobin (Hb) 7.8 g/dl (normal: 12.0–15.3 g/dl), hematocrit (Htc) 20.9 % (normal: 35–45 %), mean corpuscular volume (MCV) 86.7 fl (normal: 80–98 fl); differential blood count: 78 % neutrophils (normal: 50–75 %), 13 % lymphocytes (normal: 20–40 %); 100 ‰ reticulocytes (normal: 5–20 ‰), haptoglobin < 0.08 g/l...


TMA (thrombotic microangiopathy) TTP (thrombotic thrombocytopenic purpura) HUS (hemolytic uremic syndrome) ADAMTS-13 Complicated pregnancy Plasmapheresis 



The authors express their sincere gratitude to Eugenia Lamont for language editing of the manuscript.

Conflict of interest

All authors declare that there are no conflicts of interest.


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Copyright information

© Springer-Verlag Wien 2015

Authors and Affiliations

  • Elisabeth Fabian
    • 1
  • Florian Eisner
    • 2
  • Ingrid Pabinger
    • 3
  • Christian Viertler
    • 4
  • Sigrid Regauer
    • 4
  • Andreas Lueger
    • 2
  • Peter Neumeister
    • 5
  • Eva-Christine Weiss
    • 6
  • Wolfgang Schöll
    • 6
  • Uwe Lang
    • 6
  • Florian Prüller
    • 7
  • Guenter J. Krejs
    • 1
    Email author
  1. 1.Division of Gastroenterology and Hepatology, Department of Internal MedicineMedical University of GrazGrazAustria
  2. 2.Division of Intensive Care Medicine, Department of Internal MedicineMedical University of GrazGrazAustria
  3. 3.Department of Internal Medicine IMedical University of ViennaViennaAustria
  4. 4.Department of PathologyMedical University of GrazGrazAustria
  5. 5.Division of Hematology, Department of Internal MedicineMedical University of GrazGrazAustria
  6. 6.Department of Obstetrics and GynecologyMedical University of GrazGrazAustria
  7. 7.Department of Medical and Chemical Laboratory DiagnosticsMedical University of GrazGrazAustria

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