Clinical-Pathological Conference Series from the Medical University of Graz Case No 155: 26-year-old woman in third trimester of pregnancy with epigastric pain and thrombocytopenia
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Presentation of case
Dr. F. Eisner
Due to epigastric pain, the unemployed pregnant woman had been examined at the outpatient clinic of the Styrian Public Health Service 2 months earlier. At that time, all laboratory tests were reportedly within normal limits and the epigastric pain was said not to be unusual during pregnancy. However, when the symptoms became more severe, she presented at the Obstetrics Outpatient Clinic at the University Medical Center in Graz, where thrombocytopenia with a platelet count of 9 G/l (normal: 140–440 G/l) was diagnosed. Other laboratory test results were: leukocytes 15.6 G/l (normal: 4.4–11.3 G/l), erythrocytes 2.4 T/l (normal: 4.1–5.1 T/l), hemoglobin (Hb) 7.8 g/dl (normal: 12.0–15.3 g/dl), hematocrit (Htc) 20.9 % (normal: 35–45 %), mean corpuscular volume (MCV) 86.7 fl (normal: 80–98 fl); differential blood count: 78 % neutrophils (normal: 50–75 %), 13 % lymphocytes (normal: 20–40 %); 100 ‰ reticulocytes (normal: 5–20 ‰), haptoglobin < 0.08 g/l...
KeywordsTMA (thrombotic microangiopathy) TTP (thrombotic thrombocytopenic purpura) HUS (hemolytic uremic syndrome) ADAMTS-13 Complicated pregnancy Plasmapheresis
The authors express their sincere gratitude to Eugenia Lamont for language editing of the manuscript.
Conflict of interest
All authors declare that there are no conflicts of interest.
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