Wiener klinische Wochenschrift

, Volume 126, Issue 13–14, pp 422–426 | Cite as

May mean platelet volume levels be a predictor in the diagnosis of pelvic inflammatory disease?

  • Adnan Incebiyik
  • Ahmet Seker
  • Mehmet Vural
  • Nese Gul Hilali
  • Aysun Camuzcuoglu
  • Hakan Camuzcuoglu
original article

Summary

Background

Our aim in this study was to investigate whether mean platelet volume (MPV) value could be used as an early marker to predict pelvic inflammatory disease (PID).

Methods

Overall, 44 patients with PID and 44 healthy women were included in the study. The control group consisted of 44 women who applied to the clinic for a routine gynaecological check-up, without chronic disease or a history of medication use. Owing to the fact that it would affect thrombocyte function, women who have the following conditions were excluded from the study: women who were taking anticoagulant therapy, oral contraceptives, nonsteroid anti-inflammatory medications and who had chronic diseases. The leukocyte count, platelet count, neutrophil ratio and MPV values were collected from PID and the control group. C reactive protein values of patients with PID were also noted.

Results

MPV values in patients with PID were lower than those in the control group. This reduction in MPV is statistically significant when the PID patient group is compared with the control group (p < 0.001). A negative correlation was discovered between platelet count and MPV values (p = 0.019, r = − 0.425). Receiver-operating curve analysis pointed out that MPV has greater area under curve value than neutrophil rate, leukocyte and platelet count (0.73, 0.64, 0.72 and 0.49 respectively).

Conclusion

Since the MPV value was significantly decreased in patients with PID, it may serve as an additional and even more valuable marker than leukocyte count in the diagnosis of PID.

Keywords

Pelvic inflammatory disease Mean platelet volume Platelet C reactive protein Erythrocyte sedimentation rate 

Kann das mittlere Thrombozytenvolumen ein Prädiktor bei der Diagnose von Entzündungen im Beckenbereich sein?

Zusammenfassung

Grundlagen

Ziel dieser Studie war es zu untersuchen, ob das mittlere Thrombozytenvolumen (MPV) als früher Marker einer Erkennung von Entzündungen im Beckenbereich verwendet werden kann.

Methodik

44 Patienten mit Entzündungen im Becken und 44 gesunde Frauen wurden in die Studie aufgenommen. Die Kontrollgruppe waren Frauen, die die Ambulanz der Klinik zur gynäkologischen Routineuntersuchung aufgesucht hatten. Um andere Einflüsse auf die Thrombozytenfunktion zu vermeiden, wurden Frauen, die unter oraler Antikoagulationstherapie standen, die orale Kontrazeptiva und/oder nicht-steroidale antiinflammatorische Medikamente nahmen oder die eine chronische Erkrankung hatten, nicht in die Studie aufgenommen. Die Leukozytenzahl, die Thrombozytenzahl, der Neutrophilen Quotient und die MPV Werte wurden bei beiden Gruppen erhoben. Bei der Patientengruppe wurden zusätzlich die CRP Werte gemessen.

Ergebnisse

Die MPV Werte bei den Patientinnen waren niedriger als in der Kontrollgruppe (p < 0,001). Es bestand eine negative Korrelation zwischen der Thrombozytenzahl und den MPV Werten (p = 0,019, r = − 0,425). ROC Analysen ergaben, dass die MPV eine größere Fläche unter der Kurve hatte als die Neutrophilen Rate, oder die Leukozyten- beziehungsweise die Thrombozytenzahl (0,73, 0,64, 0,72 und 0,49 respektive).

Schlussfolgerung

Da das MPV bei Patientinnen mit Entzündungen im Beckenbereich signifikant erniedrigt war, kann dieser Parameter als ein zusätzlicher und im Vergleich zur Leukozytenzahl sogar wertvollerer Marker bei der Diagnose von Entzündungen im Beckenbereich dienen.

Schlüsselwörter

Entzündliche Erkrankungen im Becken Mittleres Thrombozytenvolumen Thrombozyten C reaktives Protein Erythrozytensenkungsgeschwindigkeit 

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Copyright information

© Springer-Verlag Wien 2014

Authors and Affiliations

  • Adnan Incebiyik
    • 1
  • Ahmet Seker
    • 2
  • Mehmet Vural
    • 1
  • Nese Gul Hilali
    • 1
  • Aysun Camuzcuoglu
    • 1
  • Hakan Camuzcuoglu
    • 1
  1. 1.Faculty of Medicine, Department of Gynecology and ObstetricsHarran University, Yenisehir CampusSanlıurfaTurkey
  2. 2.Faculty of Medicine, Department of General SurgeryHarran UniversitySanlıurfaTurkey

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