International Journal of Biometeorology

, Volume 60, Issue 1, pp 99–111 | Cite as

Biological effects of the electrostatic field: red blood cell-related alterations of oxidative processes in blood

  • Hayk A. HarutyunyanEmail author
  • Gohar V. Sahakyan
Original Paper


The aim of this study was to determine activities of pro-/antioxidant enzymes, reactive oxygen species (ROS) content, and oxidative modification of proteins and lipids in red blood cells (RBCs) and blood plasma of rats exposed to electrostatic field (200 kV/m) during the short (1 h) and the long periods (6 day, 6 h daily). Short-term exposure was characterized by the increase of oxidatively damaged proteins in blood of rats. This was strongly expressed in RBC membranes. After long-term action, RBC content in peripheral blood was higher than in control (P < 0.01) and the attenuation of prooxidant processes was shown.


  • External electrostatic field (200 kV/m) alters the balance in pro-/antioxidant processes.

  • We examine oxidative processes in plasma and RBC (hemolysate and membranes).

  • Biological effects of static electric field depend on exposure time.

  • Acute action of electrostatic field (ESF) characterized by activation of the prooxidant processes.

  • Long-term exposure reflected with prevalence of antioxidant activities.


Carbonylation of proteins Electrostatic field Oxidative processes Reactive oxygen species Red blood cells 



The research is supported by SCS MES RA, within the frames of joint Armenian—Belarusian research project No. 13РБ-047.

Conflict of interest

The authors declare that they have no competing interests.


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Copyright information

© ISB 2015

Authors and Affiliations

  1. 1.Laboratory of Biochemical and Biophysical Investigations, Scientific-Research CenterYerevan State Medical University after M. HeratsiYerevanArmenia

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