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Pediatric Nephrology

, Volume 16, Issue 7, pp 554–556 | Cite as

Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency

  • Sylvie Nathanson
  • Véronique Frémeaux-Bacchi
  • G. Deschênes
Clinical nephrology / Original Article

Abstract 

A patient with homozygous factor H deficiency presented with hemolytic uremic syndrome (HUS) at the age of 7 months. After a 2-year period of stability, renal failure and erythrocyte fragmentation recurred between the age of 3 and 4 years. Fresh frozen plasma infusions allowed renal function to be improved and erythrocyte fragmentation to be stopped. Withdrawal of plasma therapy led to a relapse of the biological signs of HUS.

Keywords Hemolytic uremic syndrome Factor H Fresh frozen plasma Renal function 

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Copyright information

© IPNA - International Pediatric Nephrology Association New York, USA 2001

Authors and Affiliations

  • Sylvie Nathanson
    • 1
  • Véronique Frémeaux-Bacchi
    • 2
  • G. Deschênes
    • 1
  1. 1.Service de Néphrologie Pédiatrique, Hôpital Armand-Trousseau, 26 avenue du Dr. Arnold-Netter, 75571 Paris cedex 12, France e-mail: georges.deschenes@trs.ap-hop-paris.fr Tel.: +33-1-44736032, Fax: +33-1-44736663FR
  2. 2.Hôpital Européen Georges Pompidou, Service d"Immunologie Biologique, 20 rue Leblanc, 75015 Paris, FranceFR

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