Pediatric Nephrology

, Volume 13, Issue 9, pp 920–925 | Cite as

Urolithiasis in Tunisian children: a study of 120 cases based on stone composition

  • Ayoub Kamoun
  • Michel Daudon
  • Jaouida Abdelmoula
  • Mourad Hamzaoui
  • Béji Chaouachi
  • Tawfik Houissa
  • Amel Zghal
  • Slim Ben Ammar
  • Chelbi Belkahia
  • Rachid Lakhoua
Original Article

Abstract 

The composition of urinary stones in children depends on socioeconomic conditions and hygiene, geographical area, and dietary habits. We analyzed urinary stones from 120 consecutive Tunisian children (81 males, 39 females) aged 5 months to 15 years. The stone was located in the upper urinary tract in 91 cases (76%). Stone analysis included both a morphological examination and an infrared analysis of the nucleus and the inner and peripheral layers. The main components of bladder calculi were whewellite (69%) and struvite (22%), whereas the main component of upper urinary tract calculi was whewellite (67%). The nucleus of bladder stones was composed of ammonium urate (45%), struvite (28%), cystine (10%), and carbapatite (7%). The nucleus of kidney and ureteral calculi was mainly composed of ammonium urate (38%), whewellite (24%), carbapatite (13%), or struvite (11%). Based on stone composition, urinary tract infection was involved in the nucleation or growth of a third of calculi. Endemic urolithiasis involving simultaneous nutritional, metabolic, and infectious factors, and defined by its nucleus composed of ammonium urate without struvite, represented 40% of cases. Exclusive metabolic factors – including genetic diseases such as primary hyperoxaluria, cystinuria, and hypercalciuria – were responsible for less than 25% of cases.

Key words Urinary calculi Stone morphology Infrared analysis Tunisia Etiology Ammonium urate 

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Copyright information

© IPNA - International Pediatric Nephrology Association New York, USA 1999

Authors and Affiliations

  • Ayoub Kamoun
    • 1
  • Michel Daudon
    • 2
  • Jaouida Abdelmoula
    • 3
  • Mourad Hamzaoui
    • 4
  • Béji Chaouachi
    • 4
  • Tawfik Houissa
    • 4
  • Amel Zghal
    • 3
  • Slim Ben Ammar
    • 3
  • Chelbi Belkahia
    • 3
  • Rachid Lakhoua
    • 1
  1. 1.Service de Pédiatrie, Hôpital Charles Nicolle, Tunis, Tunisia
  2. 2.Laboratoire CRISTAL, Service de Biochimie A, Hôpital Necker, AP-HP, Paris, FranceFR
  3. 3.Laboratoire de Biochimie, Hôpital Charles Nicolle, Tunis, Tunisia
  4. 4.Service de Chirurgie Pédiatrique, Hôpital d’Enfants, Tunis, Tunisia
  5. 5.9, Rue Imam-Sahnoun, 1002 Tunis, Tunisia Fax: +216-1-863-252

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