A rare cause of AA amyloidosis and end-stage kidney failure: Questions

  • Mehmet TaşdemirEmail author
  • Sezen Yılmaz
  • Zeliha Füsun Baba
  • Ilmay Bilge
Clinical Quiz

Case report

A 14-year-old girl presented with fatigue, diarrhea, and generalized edema lasting for 10 days. She claimed that the diarrhea is watery without any blood or mucous, in the frequency of every 2–3 h and amount of 4 kg/day. She denied any vomiting, fever, cough, and abdominal or joint pain. In her past medical history, frequent upper respiratory tract infections were notable, and she had generalized edema with no proteinuria 3 months ago before her presentation. She was not sexually active and did not smoke cigarettes, drink alcohol, or use illicit drugs. Review of family history revealed that her mother and father were cousins. There was no known family history of kidney disease or inflammatory disease.

On examination, she appeared pale. The temperature was 37.1 °C, the pulse 70 beats/min, the blood pressure 80/50 mmHg, and the respiratory rate 16 breaths/min. Her body weight was measured as 79 kg (> 95 percentile), height as 155 cm (25–50 percentile). Central obesity,...


Amyloidosis Auto inflammatory disease Children End-stage kidney failure Nephrotic syndrome 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Statement of honorarium, grant, or other form of payment to another person for manuscript preparation

The authors stated that the manuscript is of their original work and no one except the authors included into the preparation of the manuscript.


  1. 1.
    Schwartz GJ, Brion LP, Spitzer A (1987) The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin N Am 34(3):571–590CrossRefGoogle Scholar

Copyright information

© IPNA 2018

Authors and Affiliations

  1. 1.Division of Pediatric Nephrology, Department of PediatricsKoç University School of MedicineIstanbulTurkey
  2. 2.Koç University School of MedicineIstanbulTurkey
  3. 3.Department of PathologyAcıbadem Maslak HospitalIstanbulTurkey

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