Pediatric Nephrology

, Volume 27, Issue 11, pp 2007–2016 | Cite as

Continuous renal replacement therapy in children

  • Scott M. SutherlandEmail author
  • Steven R. Alexander


Over the past several decades, the epidemiology of acute kidney injury (AKI) in children has changed significantly. Pediatric patients with AKI frequently have co-morbid conditions, substantial fluid overload, and marked disease severity. At the same time, continuous renal replacement therapy (CRRT) has become the preferred modality for the management of these patients. This manuscript provides a state-of-the-art review of the technical aspects of pediatric CRRT and examines the most recent data regarding CRRT indications, timing of initiation, dosing, and outcomes in critically ill children.


Pediatric Continuous renal replacement therapy CRRT Acute kidney injury 


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Copyright information

© IPNA 2012

Authors and Affiliations

  1. 1.Department of Pediatrics, Division of NephrologyStanford University Medical CenterStanfordUSA

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