Pediatric Nephrology

, Volume 26, Issue 10, pp 1909–1912

Intensive hemodialysis for cardiomyopathy associated with end-stage renal disease

  • Edward Nehus
  • Jens Goebel
  • Mark Mitsnefes
  • Angela Lorts
  • Benjamin Laskin
Brief Report


Heart and kidney dysfunction often coexist, and increasing evidence supports the interaction of these two organs, as demonstrated by the clinical condition known as cardiorenal syndrome (CRS). We report a pediatric patient with end-stage renal disease (ESRD) who developed a dilated cardiomyopathy and decompensated heart failure after undergoing unilateral nephrectomy and while on maintenance peritoneal dialysis. He showed marked improvement in his cardiac function with the addition of intensive hemodialysis. We discuss the pathophysiology of cardiorenal syndrome in patients with ESRD and suggest that intensive dialysis may be an effective therapy for this condition.


Cardiorenal syndrome Uremia Chronic kidney disease Cardiovascular disease Echocardiogram 


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Copyright information

© IPNA 2011

Authors and Affiliations

  • Edward Nehus
    • 1
  • Jens Goebel
    • 1
  • Mark Mitsnefes
    • 1
  • Angela Lorts
    • 2
  • Benjamin Laskin
    • 1
  1. 1.Division of Nephrology and HypertensionCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  2. 2.Division of CardiologyCincinnati Children’s Hospital Medical CenterCincinnatiUSA

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