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Pediatric Nephrology

, 24:2467 | Cite as

Acute renal failure due to obstructive uric acid stones associated with acute gastroenteritis

  • Teruo Fujita
  • Takeshi Shimooka
  • Yoshie Teraoka
  • Yoshifumi Sugita
  • Hiroshi Kaito
  • Kazumoto Iijima
  • Masafumi Matsuo
  • Kandai Nozu
  • Ryojiro TanakaEmail author
Letter to the editors

Sirs,

The development of acute renal failure (ARF) in young children with acute gastroenteritis can lead to a presumptive diagnosis of pre-renal azotemia resulting from diarrheal dehydration. Recently, however, several cases of children with acute post-renal failure due to bilateral obstructive uric acid stones associated with acute gastroenteritis have been reported in Japan [1]. We have also encountered three similar cases in which the serum uric acid concentration was in the lower end of the normal range and fractional excretion of uric acid (FEUA) increased after the patients had recovered.

Case 1 was a 3-year-old boy with a 1-week history of rotavirus gastroenteritis and a 2-day history of oligouria. He was referred to our hospital for further examination of the oligouria. He had been healthy prior to the presentation of the gastroenteritis and had no familial history of urolithiasis. On admission, physical examination showed peripheral oxygen saturation (SpO 2) of between 80 and...

Keywords

Uric Acid Acute Gastroenteritis Residual Stone Serum Uric Acid Concentration Mild Dehydration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Fujinaga S, Kaneko K, Ohtomo Y, Takada M, Kobayashi K, Tada M, Yamashiro Y (2005) Acute renal failure due to obstructive uric acid stones associated with rotavirus gastroenteritis. Pediatr Nephrol 20:239–240CrossRefPubMedGoogle Scholar
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    Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H (2002) Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 417:447–452PubMedGoogle Scholar
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Copyright information

© IPNA 2009

Authors and Affiliations

  • Teruo Fujita
    • 1
  • Takeshi Shimooka
    • 1
  • Yoshie Teraoka
    • 1
  • Yoshifumi Sugita
    • 2
  • Hiroshi Kaito
    • 3
  • Kazumoto Iijima
    • 3
  • Masafumi Matsuo
    • 3
  • Kandai Nozu
    • 3
  • Ryojiro Tanaka
    • 1
    Email author
  1. 1.Department of NephrologyHyogo Prefectural Kobe Children’s HospitalSuma-ku, KobeJapan
  2. 2.Department of UrologyHyogo Prefectural Kobe Children’s HospitalSuma-ku, KobeJapan
  3. 3.Department of PediatricsKobe University Graduate School of MedicineChuo-ku, KobeJapan

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