Pediatric Nephrology

, 22:448 | Cite as

Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?

  • Michael A. Bingler
  • Demetrius Ellis
  • Michael L. MoritzEmail author
Brief Report


Acute post-streptococcal glomerulonephritis (APSGN) is rare in children under 2 years of age. This is related in part to the disease patterns of group A streptococcus (GAS) and in part to impaired immunogenicity in infants. We report the case of a 14-month-old child with APSGN following GAS pharyngitis. This case illustrates that APSGN needs to be considered in the evaluation of both gross and microscopic hematuria in this age group. We review the literature of both GAS and APSGN and discuss the pathogenesis and epidemiologic reasons for this association.


Glomerulonephritis Hematuria Proteinuria Streptococcus 


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Copyright information

© IPNA 2006

Authors and Affiliations

  • Michael A. Bingler
    • 1
  • Demetrius Ellis
    • 2
  • Michael L. Moritz
    • 2
    Email author
  1. 1.Department of Pediatrics, Children’s Hospital of PittsburghThe University of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Division of Nephrology, Children’s Hospital of PittsburghThe University of Pittsburgh School of MedicinePittsburghUSA

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