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Pediatric Nephrology

, Volume 21, Issue 6, pp 846–850 | Cite as

Health-related quality of life in pediatric patients with ESRD

  • Stuart L. GoldsteinEmail author
  • Nicole Graham
  • Tasha Burwinkle
  • Bradley Warady
  • Rhonda Farrah
  • James W. Varni
Original Article

Abstract

As part of creating a pediatric ESRD-specific Health-Related Quality of Life (HRQOL) assessment instrument, we established pilot data with the PedsQL 4.0 Generic Core Scales in 96 pediatric patients with ESRD receiving hemodialysis (HD), peritoneal dialysis (PD) or with a renal transplant (TX). Patient age ranges were: 2–4 (8; PD n=3, TX n=5), 5–7 (12; HD n=9, TX n=3), 8–12 (25; HD n=5, PD n=6, TX n=14), 13–18 (51; HD n=18, PD n=10, TX n=23). PedsQL ESRD data were compared to healthy children (n=131 child report; n=145 parent report) and across HD/PD/TX. For all domains, ESRD patient HRQOL scores were significantly lower than healthy controls. Transplant patients reported better physical and psychosocial health than dialysis patients. No difference was noted between HD and PD patients for any PedsQL domain. Our data demonstrate that the PedsQL 4.0 Generic Core Scales is a useful measurement instrument to screen for HRQOL impairment in pediatric patients with ESRD. We suggest that the ESRD-specific HRQOL instrument in development is needed to help define condition-specific HRQOL differences between modalities.

Keywords

Children Chronic kidney disease Health related quality of life 

Notes

Acknowledgements

The manuscript is dedicated to the memory of Rhonda Farrah, RN, whose commitment to the project was essential to its successful completion.

This work was supported by the Franklin McDonald/Fresenius Medical Care Clinical Research Award of the National Kidney Foundation.

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Copyright information

© IPNA 2006

Authors and Affiliations

  • Stuart L. Goldstein
    • 1
    Email author
  • Nicole Graham
    • 1
  • Tasha Burwinkle
    • 2
  • Bradley Warady
    • 3
  • Rhonda Farrah
    • 3
  • James W. Varni
    • 4
    • 5
  1. 1.Texas Children’s HospitalHoustonUSA
  2. 2.University of WashingtonWashingtonUSA
  3. 3.Children’s Mercy Hospital and ClinicsKansasUSA
  4. 4.Department of PediatricsCollege of MedicineTexasUSA
  5. 5.Department of Landscape Architecture and Urban Planning, College of ArchitectureTexas A&M UniversityTexasUSA

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