Pediatric Nephrology

, Volume 19, Issue 4, pp 448–450 | Cite as

Acute renal failure associated with Gemella haemolysans pneumonia

  • Michael Eisenhut
  • Caroline Jones
  • David Hughes
  • Simon Herrington
  • George Kokai
Brief Report


We describe a 13-year-old boy who developed acute renal failure associated with Gemella haemolysans pneumonia. At presentation he was found to have macroscopic hematuria associated with lobar pneumonia. Gemella haemolysans was isolated from blood cultures. Renal failure was detected on admission, progressed and dialysis was required until day 18. Renal impairment had resolved by 3 months after the initial presentation. Histopathology of a renal biopsy showed focal proliferative glomerulonephritis, but the predominant abnormality was tubular damage associated with erythrocyte casts in tubular lumina. We believe that tubular damage due to hematuria rather than the glomerular changes was the most likely cause of renal failure.


Gemella Focal proliferative glomerulonephritis Renal failure Macroscopic hematuria Pneumonia 


  1. 1.
    Srivstava T, Warady BA, Alon US (2002) Pneumonia-associated acute glomerulonephritis. Clin Nephrol 57:175–182PubMedGoogle Scholar
  2. 2.
    Garcia-Lechuz JM, Cuevas-Lobato O, Hernangomez S, Hermida A, Guinea J, Marin M, Pelaez T, Bouza E (2002) Extra-abdominal infections attributable to Gemella species. Int J Infect Dis 6:78–82PubMedGoogle Scholar
  3. 3.
    Zingaro L, Bartoli E, Sechi LA (1999) Post-infectious glomerulonephritis in a patient with Gemella haemolysans endocarditis. Am J Med 106:125–126Google Scholar
  4. 4.
    Schachter U, Pomeranz A, Berger I, Wolach B (1987) Acute glomerulonephritis secondary to lobar pneumonia. Int J Pediatr Nephrol 8:211–214PubMedGoogle Scholar
  5. 5.
    Van Westrhenen R, Weening JJ, Krediet RT (1998) Pneumonia and glomerulonephritis caused by Mycoplasma pneumoniae. Nephrol Dial Transplant 13:3208–3211CrossRefPubMedGoogle Scholar
  6. 6.
    Nagashima T, Hirata D, Yamamoto H, Okazaki H, Minota S (2001) Antineutrophil cytoplasmic autoantibody specific for proteinase 3 in a patient with shunt nephritis induced by Gemella morbillorum. Am J Kidney Dis 37:E1−E6Google Scholar
  7. 7.
    Fogazzi GB, Imbasciati E, Moroni G, Scalia A, Mihatsch MJ, Ponticelli C (1995) Reversible acute renal failure from gross haematuria due to glomerulonephritis: not only in IgA nephropathy and not associated with intratubular obstruction. Nephrol Dial Transplant 10:624–629PubMedGoogle Scholar
  8. 8.
    Praga M, Gutierrez-Millet V, Navas JJ, Ruilope LM, Morales JM, Alcazar JM, Bello I, Rodicio JL (1985) Acute worsening of renal function during episodes of macroscopic hematuria in IgA nephropathy. Kidney Int 28:69–74PubMedGoogle Scholar

Copyright information

© IPNA 2004

Authors and Affiliations

  • Michael Eisenhut
    • 1
    • 4
  • Caroline Jones
    • 1
  • David Hughes
    • 1
  • Simon Herrington
    • 2
  • George Kokai
    • 3
  1. 1.Royal Liverpool Children’s HospitalLiverpoolUK
  2. 2.Department of PathologyRoyal Liverpool University HospitalLiverpoolUK
  3. 3.Department of HistopathologyRoyal Liverpool Children’s HospitalLiverpoolUK
  4. 4.LiverpoolUK

Personalised recommendations