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Pediatric Nephrology

, Volume 19, Issue 2, pp 227–228 | Cite as

Muscle involvement in a patient with Henoch-Schönlein purpura nephritis

  • Toru WatanabeEmail author
  • Yuki Abe
Brief Report

Abstract

Although Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis affecting multiple organ systems, muscle involvement has rarely been reported. This report describes muscle pain and weakness in a patient with HSP nephritis (HSPN). A 13-year-old boy suffered from purpura, abdominal pain, and symmetrical muscle pain and weakness of the extremities. He was diagnosed as having HSP with muscle involvement. His abdominal pain and muscle involvement improved 1 week after commencing oral prednisolone therapy. The patient subsequently developed biopsy proven HSPN. It should be noted that, although rare, muscle involvement might occur in HSP as in other systemic vasculitides. The precise pathogenic mechanism underlying its development is currently unclear.

Keywords

Myalgia Muscle pain Muscle weakness Henoch-Schönlein purpura Vascular purpura Vasculitis 

References

  1. 1.
    Gairdner D (1948) The Schönlein-Henoch syndrome (anaphylactoid purpura). Q J Med 17:95–122Google Scholar
  2. 2.
    Robson WLM, Leung AKC (1994) Henoch-Schönlein purpura. Adv Pediatr 41:163–194PubMedGoogle Scholar
  3. 3.
    Szer IS (1994) Henoch-Schönlein purpura. Curr Opin Rheumatol 6:25–31PubMedGoogle Scholar
  4. 4.
    Allen DM, Diamond LK, Howell DA (1960) Anaphylactoid purpura in children (Schönlein-Henoch syndrome). Am J Dis Child 99:833–854Google Scholar
  5. 5.
    Meadow R (1979) Schönlein-Henoch syndrome. Arch Dis Child 54:822–824PubMedGoogle Scholar
  6. 6.
    Somekh E, Fried D, Hanukoglu A (1983) Muscle involvement in Schönlein-Henoch syndrome. Arch Dis Child 58:929–930PubMedGoogle Scholar
  7. 7.
    White RHR (1991) Henoch-Schönlein purpura. In: Churg A, Churg J (eds) Systemic vasculitides. Igaku-Shoin, New York, pp 203–217Google Scholar
  8. 8.
    Cuttica RJ (1997) Vasculitis in children: a diagnostic challenge. Curr Probl Pediatr 27:309–318PubMedGoogle Scholar
  9. 9.
    Jennette JC, Falk RJ (1997) Small-vessel vasculitis. N Engl J Med 337:1512–1523PubMedGoogle Scholar

Copyright information

© IPNA 2004

Authors and Affiliations

  1. 1.Department of PediatricsNiigata City General HospitalJapan

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