Surgical Endoscopy

, Volume 33, Issue 7, pp 2083–2092 | Cite as

Short-term outcomes of laparoscopic repeat liver resection after open liver resection: a systematic review

  • Taiga Wakabayashi
  • Emanuele Felli
  • Riccardo Memeo
  • Pietro Mascagni
  • Yuta Abe
  • Yuko Kitagawa
  • Patrick PessauxEmail author
Review Article



Laparoscopic repeat liver resection (LRLR) still represents a challenge for surgeons especially in case with previous open liver surgery. The aim of the study is to perform a systematic review of the current literature to investigate the feasibility of LRLR after open liver resection (OLR) for liver diseases.


A computerized search was performed for all English language studies evaluating LRLR. A meta-analysis was performed to evaluate the short-term outcomes in comparative studies between LRLR with previous laparoscopic liver resection (LLR) and OLR.


From the initial 55 manuscripts, 8 studies including 3 comparative studies between LRLR after OLR and LLR were investigated. There was a total of 108 patients. Considering initial surgery, the extent of initial liver resection was major liver resection in 20% of patients in whom it was reported. In all the patients, the most frequent primary histology was hepatocellular carcinoma, followed by colorectal liver metastasis. A half of reported patients had severe adhesions at the time of LRLR. The median operative time for LRLR was ranged from 120 to 413 min and the median blood loss ranged from 100 to 400 mL. There were 11% of the patients conversions to open surgery, hand-assisted laparoscopic surgery, or tumor ablation. The overall postoperative morbidity was 15% of all the patients, and there was no postoperative mortality. The median postoperative hospital stay was ranged from 3.5 to 10 days. The meta-analysis shows that LRLR after OLR is associated with a longer operative time and a more important blood loss compared to LRLR after LLR. However, no difference between LRLR after OLR and LLR was shown as far as hospital stay and morbidity rate are concerned.


LRLR after OLR has been described in eight articles with favorable short-term outcomes in highly selected patients.


Laparoscopy Repeat liver resection Repeat hepatectomy Redo liver surgery Previous open liver resection Short-term outcomes 



Authors are grateful to Christopher Burel and Guy Temporal for their assistance in proofreading the manuscript.

Compliance with ethical standards


Dr. Taiga Wakabayashi, Dr. Emanuele Felli, Dr. Riccardo Memeo, Dr. Pietro Mascagni, Dr. Yuta Abe, Dr. Yuko Kitagawa, and Dr. Patrick Pessaux have no conflicts of interest or financial ties to disclose.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Taiga Wakabayashi
    • 1
    • 2
  • Emanuele Felli
    • 1
    • 3
    • 5
  • Riccardo Memeo
    • 1
    • 3
    • 4
    • 5
  • Pietro Mascagni
    • 5
  • Yuta Abe
    • 2
  • Yuko Kitagawa
    • 2
  • Patrick Pessaux
    • 1
    • 3
    • 5
    Email author
  1. 1.Institut de Recherche Contre les Cancers de l’Appareil Digestif (IRCAD)StrasbourgFrance
  2. 2.Department of SurgeryKeio University School of MedicineTokyoJapan
  3. 3.Department of General, Digestive, and Endocrine Surgery, Nouvel Hôpital CivilUniversité de StrasbourgStrasbourgFrance
  4. 4.Department of Emergency and Organ TransplantationUniversity Aldo Moro of BariBariItaly
  5. 5.Institute of Minimally Invasive Hybrid Image-Guided SurgeryInstitut Hospitalo-Universitaire (IHU), Université de StrasbourgStrasbourgFrance

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