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Surgical Endoscopy

, Volume 32, Issue 11, pp 4393–4401 | Cite as

The impact of preoperative carbohydrate loading on intraoperative body temperature: a randomized controlled clinical trial

  • Hiroki Hamamoto
  • Masashi Yamamoto
  • Shinsuke Masubuchi
  • Masatsugu Ishii
  • Wataru Osumi
  • Keitaro Tanaka
  • Junji Okuda
  • Kazuhisa Uchiyama
Article

Abstract

Background

Preoperative carbohydrate loading (CHO) is one element of the enhanced recovery after surgery protocol. No clinical trial has investigated the impact of preoperative CHO on intraoperative body temperature.

Methods

This study was a single-center, prospective, randomized controlled clinical trial involving patients undergoing laparoscopic colon cancer surgery. The primary end point was the intraoperative core temperature during surgery, which was measured at 30-min intervals for 150 min after starting surgery. The secondary end points were short-term outcomes and body composition changes.

Results

From July 2013 to May 2014, we randomized 70 patients into the control group (n = 33) or CHO group (n = 31); six patients were excluded. The core temperature of the CHO group 90, 120, and 150 min after starting surgery was significantly lower than that of the control group (control vs. CHO, respectively: 90 min; 36.26 ± 0.41 vs. 36.05 ± 0.43 °C, p = 0.0233, 120 min; 36.30 ± 0.44 vs. 36.06 ± 0.50 °C, p = 0.0283, 150 min; 36.33 ± 0.50 vs. 36.01 ± 0.56 °C, p = 0.0186). We also found a significant difference in body weight loss (control vs. CHO, respectively: − 1.6 ± 0.8 vs. − 0.9 ± 1.4 kg, p = 0.0304) and loss of lower limb muscle mass (− 0.7 ± 0.7 vs. − 0.3 ± 0.6 kg, p = 0.0110) between the control and CHO groups, respectively.

Conclusion

CHO had no effect on raising the intraoperative core temperature, and no negative impact on the perioperative outcome. CHO prevented the loss of lower limb muscle mass, which may lead to better postoperative recovery.

Keywords

Enhanced recovery after surgery Preoperative carbohydrate loading Intraoperative core temperature Laparoscopic colon cancer surgery 

Notes

Compliance with ethical standards

Disclosures

Drs. Hiroki Hamamoto, Masashi Yamamoto, Shinsuke Masubuchi, Masatsugu Ishii, Wataru Osumi, Keitaro Tanaka, Junji Okuda, and Kazuhisa Uchiyama have no conflicts of interest or financial ties to disclose.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of General and Gastroenterological SurgeryOsaka Medical CollegeTakatsukiJapan

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