The feasibility and efficacy of pure laparoscopic repeat hepatectomy
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Repeat hepatectomy is often required for hepatocellular carcinoma and metastatic tumors. However, this procedure is technically challenging, so laparoscopic repeat hepatectomy (LRH) has not been widely adopted. The aim of this study was to evaluate the feasibility and efficacy of LRH compared with open repeat hepatectomy (ORH) and laparoscopic primary hepatectomy (LPH).
We introduced laparoscopic hepatectomy at our institution in April 2014. We performed 127 LPH (LPH group) and 33 LRH procedures (LRH group) from April 2014 to April 2017; 37 patients underwent ORH from January 2010 to April 2017 (ORH group). This study retrospectively compared the patient characteristics and short-term outcomes of the LRH and ORH groups as well as the LRH and LPH groups.
There were no conversions to open surgery in the LRH group. In comparing the LRH and ORH groups, there were no significant differences in patient characteristics except for the type of approach to the previous hepatectomy (p = 0.004) and indocyanine green retention rate at 15 min (median 12.5 vs. 8.75%, p = 0.026). The LRH group had less blood loss (median 30 mL vs. 652 mL; p < 0.001), less intraoperative transfusion (6.1 vs. 32.4%; p = 0.006), and shorter postoperative hospital stays (median 6.5 days vs. 9.0 days; p < 0.001). There were no differences with regard to operation time, severe postoperative complications, and mortality. In comparing the LRH and LPH groups, there was a significant difference only in past history of abdominal surgery (100 vs. 61.4%; p < 0.001). In the short-term outcomes, the postoperative hospital stay was significantly shorter in the LRH group (median 6.5 days vs. 7 days; p = 0.033), and the other results were comparable between the two groups.
LRH is feasible and useful for repeat hepatectomy, achieving good short-term outcomes.
KeywordsLaparoscopic hepatectomy Laparoscopic liver resection Repeat hepatectomy Rehepatectomy Hepatocellular carcinoma Metastatic tumor
Compliance with ethical standards
Drs. Yusuke Ome, Kazuki Hashida, Mitsuru Yokota, Yoshio Nagahisa, Kazushige Yamaguchi, Michio Okabe, and Kazuyuki Kawamoto have no conflicts of interest or financial ties to disclose.
- 3.Petrowsky H, Gonen M, Jarnagin W, Lorenz M, DeMatteo R, Heinrich S, Encke A, Blumgart L, Fong Y (2002) Second liver resections are safe and effective treatment for recurrent hepatic metastases from colorectal cancer: a bi-institutional analysis. Ann Surg 235:863–871CrossRefPubMedPubMedCentralGoogle Scholar
- 11.de Jong MC, Mayo SC, Pulitano C, Lanella S, Ribero D, Strub J, Hubert C, Gigot JF, Schulick RD, Choti MA, Aldrighetti L, Mentha G, Capussotti L, Pawlik TM (2009) Repeat curative intent liver surgery is safe and effective for recurrent colorectal liver metastasis: results from an international multi-institutional analysis. J Gastrointest Surg 13:2141–2151CrossRefPubMedGoogle Scholar
- 19.Isetani M, Morise Z, Kawabe N, Tomishige H, Nagata H, Kawase J, Arakawa S (2015) Pure laparoscopic hepatectomy as repeat surgery and repeat hepatectomy. World J Surg 21:961–968Google Scholar