Design of wormlike automated robotic endoscope: dynamic interaction between endoscopic balloon and surrounding tissues
- 591 Downloads
The current design of capsule endoscope is limited by the inability to control the motion within gastrointestinal tract. The rising incidence of gastrointestinal cancers urged improvement in the method of screening endoscopy.
This preclinical study aimed to design and develop a novel locomotive module for capsule endoscope. We investigated the feasibility and physical properties of this newly designed caterpillar-like capsule endoscope with a view to enhancing screening endoscopy.
This study consisted of preclinical design and experimental testing on the feasibility of automated locomotion for a prototype caterpillar endoscope. The movement was examined first in the PVC tube and then in porcine intestine. The image captured was transmitted to handheld device to confirm the control of movement. The balloon pressure and volume as well as the contact force between the balloon and surroundings were measured when the balloon was inflated inside (1) a hard PVC tube, (2) a soft PVC tube, (3) muscular sites of porcine colons and (4) less muscular sites of porcine colons.
The prototype caterpillar endoscope was able to move inward and backward within the PVC tubing and porcine intestine. Images were able to be captured from the capsule endoscope attached and being observed with a handheld device. Using the onset of a contact force as indication of the buildup of the gripping force between the balloon and the lumen walls, it is concluded from the results of this study that the rate of change in balloon pressure and volume is two good estimators to optimize the inflation of the balloon.
The results of this study will facilitate further refinement in the design of caterpillar robotic endoscope to move inside the GI tract.
KeywordsCapsule endoscope Robotic endoscope Locomotive module
This work was supported by the Hong Kong Innovation and Technology Commission (ITS/197/12) and CUHK Direct Grant (No. 4054058).
Carmen C. Y. Poon, Billy Leung, Cecilia K. W. Chan, James Y. W. Lau and Philip W. Y. Chiu declared no conflict of interest.
Supplementary material 1 (MP4 89614 kb)
- 2.Leung WK, Ho SS, Suen BY, Lai LH, Yu S, Ng EK, Ng SS, Chiu PW, Sung JJ, Chan FK, Lau JY (2012) Capsule endoscopy or angiography in patients with acute overt obscure gastrointestinal bleeding: a prospective randomized study with long-term follow-up. Am J Gastroenterol 107(9):1370–1376CrossRefPubMedGoogle Scholar
- 12.Sung JJ, Ng SC, Chan FK, Chiu HM, Kim HS, Matsuda T, Ng SS, Lau JY, Zheng S, Adler S, Reddy N, Yeoh KG, Tsoi KK, Ching JY, Kuipers EJ, Rabeneck L, Young GP, Steele RJ, Lieberman D, Goh KL (2014) An updated Asia Pacific Consensus Recommendations on colorectal cancer screening. Gut. doi: 10.1136/gutjnl-2013-306503
- 13.Nishihara R, Wu K, Lochhead P, Morikawa T, Liao X, Qian ZR, Inamura K, Kim SA, Kuchiba A, Yamauchi M, Imamura Y, Willett WC, Rosner BA, Fuchs CS, Giovannucci E, Ogino S, Chan AT (2013) Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med 369(12):1095–1105CrossRefPubMedGoogle Scholar
- 14.Senore C, Armaroli P, Silvani M, Andreoni B, Bisanti L, Marai L, Castiglione G, Grazzini G, Taddei S, Gasperoni S, Giuliani O, Malfitana G, Marutti A, Genta G, Segnan N (2010) Comparing different strategies for colorectal cancer screening in Italy: predictors of patients’ participation. Am J Gastroenterol 105(1):188–198CrossRefPubMedGoogle Scholar