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Surgical Endoscopy

, Volume 28, Issue 9, pp 2584–2591 | Cite as

Laparoscopic versus open distal splenopancreatectomy for the treatment of pancreatic body and tail cancer: a retrospective, mid-term follow-up study at a single academic tertiary care institution

  • Minggen Hu
  • Guodong Zhao
  • Fei Wang
  • Zhiming Zhao
  • Chenggang Li
  • Rong Liu
Article

Abstract

Background/Objective

Laparoscopic distal splenopancreatectomy (DSP) is an effective and safe surgical modality for treating benign and borderline distal pancreatic tumors, but rarely for pancreatic cancer. This study aimed to examine the feasibility, effectiveness, and safety of laparoscopic versus laparotomic DSP in pancreatic body-tail cancer (PBTC) patients.

Methods

Thirty-four PBTC patients were consecutively and retrospectively hospitalized for elective laparoscopic DSP (n = 11) or laparotomy (n = 23) between January 2007 and December 2011. The primary outcome measure was mean overall survival (OS).

Results

All patients underwent DSP via laparoscopy or laparotomy as scheduled and were followed-up for 12–72 months. The two groups showed statistically similar mean operative time (laparoscopy vs. laparotomy, 150 ± 54 vs. 160 ± 48 min), median volume of intraoperative bleeding (100 [50–400] vs. 150 [50–350] ml), and rate of postoperative pancreatic fistula (18.2 vs. 21.7 %). The laparoscopy group had a significantly shorter median duration of hospitalization (5 [3–12] vs. 8 [7–22] d, P < 0.05). All patients had a clear resection margin and showed statistically similar tumor size (2.8 ± 1.5 vs. 3.1 ± 1.7 cm), number of lymph nodes dissected (14.8 ± 4.5 vs. 16.1 ± 5.7), and mean OS (42.0 ± 8.6 vs. 54.0 ± 5.8 mo, P > 0.05).

Conclusions

Laparoscopic DSP is a feasible, effective, and safe alternative to laparotomy in carefully selected PBTC patients and is associated with a more rapid postoperative recovery.

Keywords

Pancreatic cancer Splenopancreatectomy Laparoscopy Radical resection Comparative study 

Notes

Acknowledgments

This study was supported by the Beijing Nova Program (Grant No. 2012077) and the Beijing Special Clinical Application Program (Grant No. Z121107001012133).

Disclosures

Drs. Minggen Hu, Guodong Zhao, Fei Wang, Zhiming Zhao, Chenggang Li, Zhipeng Zhou, Dabin Xu, Yong Xu, Dongda Song and Rong Liu have no conflicts of interest or financial ties to disclose.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Minggen Hu
    • 1
  • Guodong Zhao
    • 1
  • Fei Wang
    • 1
  • Zhiming Zhao
    • 1
  • Chenggang Li
    • 1
  • Rong Liu
    • 1
  1. 1.Department of Surgical OncologyThe General Hospital of Chinese People’s Liberation ArmyBeijingChina

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