Surgical Endoscopy

, Volume 27, Issue 7, pp 2598–2605 | Cite as

Comparison of short- and long-term outcomes of laparoscopic-assisted total gastrectomy and open total gastrectomy in gastric cancer patients

  • Moon-Soo Lee
  • Ju-Hee Lee
  • Do Joong Park
  • Hyuk-Joon Lee
  • Hyung-Ho Kim
  • Han-Kwang Yang
Article

Abstract

Background

Laparoscopy-assisted total gastrectomy (LATG) has been used more frequently despite the associated technical difficulty and concerns over oncological safety. This study was undertaken to compare the short- and long-term surgical outcomes following either LATG or open total gastrectomy (OTG) for gastric cancer.

Methods

A total of 120 LATG and 228 OTG were retrospectively matched with respect to sex, age (±5 years), and pathological tumor-node-metastasis stage for comparison of the clinical outcomes.

Results

The total complication rate among 120 LATG and 228 OTG was 18.3 % (22/120) and 16.2 % (37/228), respectively. The most common complication after LATG was anastomotic-related complication (6.7 %); five anastomotic leakages (4.2 %) and three anastomotic strictures were reported (2.5 %). That after OTG was wound complication (3.5 %), including seroma or infection. Matched patients analysis: Time to first gas passing and time to the resumption of a soft diet were significantly shorter in the LATG group than in the OTG group. The postoperative hospital stay of LATG was shorter in the LATG group (9.3 ± 4.2 days) than in the OTG group (11.7 ± 7.3 days; p = 0.057). Among matched patients, there was no significant difference between complication rate (24 vs. 32 %; p = 0.504) or leakage rate (6 vs. 4 %). During median follow-up of 50 (range, 10–92) months, there was no significant difference in the disease-free survival rate between the matched groups, respectively (94.5 vs. 87.1 %: p = 0.148). As for patients with TNM stage I gastric cancer, the disease-free survival rate (100 vs. 90.9 %; p = 0.5) and the cumulative survival rate (91.5 vs. 95.2 %; p = 0.618) did not differ significantly between the LATG and OTG groups.

Conclusions

LATG for gastric cancer has the advantage over an OTG in terms of better short-term outcomes and similar long-term outcome. LATG is an acceptable alternative to OTG for the treatment of gastric cancer.

Keywords

Total gastrectomy Laparoscopy Gastric cancer 

Notes

Disclosures

Drs. M.-S. Lee, J.-H. Lee, D. J. Park, H.-J. Lee, H.-H. Kim, and H.-K. Yang have no conflicts of interest or financial ties to disclose.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Moon-Soo Lee
    • 2
    • 3
  • Ju-Hee Lee
    • 2
  • Do Joong Park
    • 1
    • 2
  • Hyuk-Joon Lee
    • 1
  • Hyung-Ho Kim
    • 1
    • 2
  • Han-Kwang Yang
    • 1
  1. 1.Department of SurgerySeoul National University College of MedicineSeoulSouth Korea
  2. 2.Department of SurgerySeoul National University Bundang HospitalSeongnamSouth Korea
  3. 3.Eulji University HospitalDaejeonSouth Korea

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