Surgical Endoscopy

, Volume 25, Issue 2, pp 543–548

Endoscopic mucosal resection for gastroesophageal cancer in a U.K. population. Long-term follow-up of a consecutive series

  • Andrew B. C. Crumley
  • James J. Going
  • Kerryanne McEwan
  • Margaret McKernan
  • Jo-Etienne Abela
  • Christopher J. Shearer
  • Adrian J. Stanley
  • Robert C. Stuart
Article

Abstract

Background

Endoscopic mucosal resection (EMR) of early gastric and esophageal tumors is effective and avoids the morbidity and mortality of surgery. We report the long-term results of a consecutive series of 93 endoscopic resections, during a 7-year period, in a U.K. population.

Methods

Eighty-eight patients with 93 lesions were included. EMR was performed for 64 and 29 malignant and benign lesions, respectively. Patients with malignant disease were subgrouped into “high risk” or “low risk” for recurrence.

Results

Of the 35 lesions in the low-risk group, local control was achieved in 31; 29 after 1 EMR session. Two had residual invasive carcinoma, one had treatment ceased due to pancreatic cancer, and one patient did not attend follow-up. Of the 29 lesions in the high-risk group, local control was achieved in 15; 13 after 1 EMR session. Median follow-up was 53 months. Cancer specific survival for the 45 invasive cancers (T1m and T1sm) was 93%; three patients died from their disease.

Conclusions

This study has shown for the first time in a U.K. population that EMR is effective in controlling disease in patients with local high grade dysplasia (HGD) and early invasive carcinoma, with no mortality and low morbidity.

Keywords

Gastric Esophageal Cancer Barrett’s Endoscopy 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Andrew B. C. Crumley
    • 1
  • James J. Going
    • 2
  • Kerryanne McEwan
    • 2
  • Margaret McKernan
    • 1
  • Jo-Etienne Abela
    • 1
  • Christopher J. Shearer
    • 1
  • Adrian J. Stanley
    • 3
  • Robert C. Stuart
    • 1
  1. 1.University Department of SurgeryRoyal InfirmaryGlasgowUK
  2. 2.University Department of PathologyRoyal InfirmaryGlasgowUK
  3. 3.University Department of MedicineRoyal InfirmaryGlasgowUK

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