Laparoscopic sleeve gastrectomy as first stage or definitive intent in 300 consecutive cases
Laparoscopic sleeve gastrectomy (SG) was originally used as a bridge to definitive surgery in high-risk patients. Recently it has been considered as a stand-alone procedure due to its effectiveness on weight loss and comorbidities resolution. This study was designed to evaluate the results of SG on complications, body mass index (BMI), and comorbidities resolution in 300 consecutive obese patients and to analyze the lesson learned from this experience.
From October 2002 to November 2009, 300 patients underwent SG. In the first 100 cases (group 1: mean BMI, 54.4 ± 9.3), SG was intended as a first stage of biliopancreatic diversion with duodenal switch in high risk super-obese patients. In the last 200 cases (group 2: mean BMI, 45.5 ± 7.3), SG was intended as a definitive procedure. No routine reinforcement was performed in group 1. In group 2, oversewn reinforcement was performed routinely. SG was redo surgery in 21 patients (7%).
Mean operative time was 119 ± 48.6 min in group 1 and 72 ± 33.8 in group 2. Conversion rate was 0.6% (massive hepatomegaly). Mortality was 0.6%. Major postoperative complications were registered in 15 patients in group 1 and 11 in group 2. In 3 cases, a reoperation was needed. The mean BMI in group 1 was 46, 43, 39, and 31 at 6, 12, 24, and 36 months, respectively. In group 2, the mean BMI was 32.9, 30.6, and 31.7 at 6, 12, and 18 months. At 12 months, the diabetes, hypertension, and OSAS were cured on 69%, 62%, and 50% in group 1 and 88%, 57%, and 58% in group 2. In group 2, no patient required second stage.
SG is a safe and effective treatment for morbid obesity at mid-term follow-up. SG is effective for comorbidities resolution, especially for the treatment of diabetes. Suture line reinforcement allows a significant reduction of bleeding.
KeywordsMorbid obesity Sleeve gastrectomy Bariatric surgery
Drs. Nicola Basso, Giovanni Casella, Mario Rizzello, Francesca Abbatini, Emanuele Soricelli, Giorgio Alessandri, Cristina Maglio, and Aldo Fantini have no conflicts of interest or financial ties to disclose.
- 6.Silecchia G, Boru C, Pecchia A, Rizzello M, Casella G, Leonetti F, Basso N (2006) Effectiveness of laparoscopic sleeve gastrectomy (first stage of biliopancreatic diversion with duodenal switch) on co-morbidities in super-obese high-risk patients. Obes Surg 16(9):1138–1144CrossRefPubMedGoogle Scholar
- 14.Karamanakos SN, Vagenas K, Kalfarentzos F, Alexandrides TK (2008) Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg 247(3):408–410CrossRefGoogle Scholar
- 15.Soricelli E, Casella G, Rizzello M Calì B, Alessandri G, Basso N (2010) Initial experience with laparoscopic crural closure in the management of hiatal hernia in obese patients undergoing sleeve gastrectomy. Obes Surg (Epub ahead of print)Google Scholar
- 23.Croce E, Olmi S (2006) Chirurgia del reflusso gastroesofageo UTET, Torino, p 18Google Scholar