Surgical Endoscopy

, Volume 23, Issue 7, pp 1564–1568

Laparoscopic versus open live donor nephrectomy: outcomes analysis of 266 consecutive patients

  • Charles J. Dolce
  • Jennifer E. Keller
  • K. Christian Walters
  • Daniel Griffin
  • H. James Norton
  • B. Todd Heniford
  • Kent W. Kercher
Article

DOI: 10.1007/s00464-009-0340-7

Cite this article as:
Dolce, C.J., Keller, J.E., Walters, K.C. et al. Surg Endosc (2009) 23: 1564. doi:10.1007/s00464-009-0340-7

Abstract

Background

Minimally invasive surgical techniques have become the preferred method for live donor nephrectomy (DN) in many centers. We compared our experience with laparoscopic and open DN in a single institution.

Methods

Data for 266 consecutive live DNs were collected. Demographic, intraoperative, and postoperative data were compared.

Results

A total of 199 hand-assisted laparoscopic (HAL) DNs, 18 totally laparoscopic (TL), and 49 open DNs were performed. Laparoscopic DN was associated with a shorter operative time (p < 0.013), less blood loss (p < 0.0001), and shorter hospital stay (p < 0.0001) than open DN. Warm ischemia time was less for HAL versus TL DN (59.9 vs. 90.0 seconds; p < 0.0001). Compared with open DN, laparoscopic patients had fewer complications (p < 0.03), fewer wound infections (p < 0.004), less wound paresthesias (p < 0.0009), and fewer complaints of chronic incisional pain (p < 0.0001). Delayed graft function during the first 24 h postoperatively was significantly less for the laparoscopic DN versus the open cases (12.9% vs. 30.4%; p = 0.003), but the need for hemodialysis for the recipient was similar between groups (6.9% vs. 5%; p = not significant).

Conclusions

Laparoscopic DN resulted in less blood loss, reduced operative time, and shorter hospital stay than open DN. Hand-assisted laparoscopic DN has the potential to decrease warm ischemia time for renal allografts. Donors managed laparoscopically had fewer complications, significantly less wound-related morbidity, and less delayed graft function than patients who underwent open DN.

Keywords

Donor nephrectomy Laparoscopic Outcomes Delayed graft function 

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Charles J. Dolce
    • 1
  • Jennifer E. Keller
    • 1
  • K. Christian Walters
    • 1
  • Daniel Griffin
    • 1
  • H. James Norton
    • 1
  • B. Todd Heniford
    • 1
  • Kent W. Kercher
    • 1
  1. 1.Department of Surgery, Division of Gastrointestinal and Minimally Invasive SurgeryCarolinas Medical CenterCharlotteUSA 

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