Surgical Endoscopy

, Volume 23, Issue 8, pp 1908–1913 | Cite as

Endoscopic full-thickness resection with laparoscopic assistance as hybrid NOTES for gastric submucosal tumor

  • Nobutsugu AbeEmail author
  • Hirohisa Takeuchi
  • Osamu Yanagida
  • Tadahiko Masaki
  • Toshiyuki Mori
  • Masanori Sugiyama
  • Yutaka Atomi


Background and objective

Laparoscopic wedge resection using a linear stapler is widely accepted as a treatment for gastric submucosal tumor (SMT). Although this surgery is simple, it can lead to excessive normal tissue removal. To avoid the latter, we have introduced endoscopic full-thickness resection with laparoscopic assistance, known as laparoscopy-assisted endoscopic full-thickness resection (LAEFR). Herein, we present the preliminary results of LAEFR for gastric SMT patients.


Four patients with gastric SMT underwent LAEFR. LAEFR consists of four major procedures: (1) a circumferential incision as deep as the submucosal layer around the lesion by the endoscopic submucosal dissection technique, (2) endoscopic full-thickness (from the muscle layer to the serosal layer) incision around the three-fourths or two-thirds circumference on the above-mentioned submucosal incision under laparoscopic supervision, (3) completion of the full-thickness incision laparoscopically from inside the peritoneal cavity, and (4) handsewn closure of the gastric-wall defect.


LAEFR was successfully carried out without any intraoperative or postoperative adverse events. Mean operating time and estimated blood loss were 201 min and 27 mL, respectively. Contrast roentgenography on postoperative day 3 showed neither gastric deformity nor disturbance of gastric emptying in all the patients.


LAEFR may be considered one of the so-called hybrid natural orifice translumenal endoscopic surgery (NOTES) techniques because a peroral endoscope advances into the peritoneal cavity. LAEFR enabled whole-layer excision as small as possible with an adequate margin. LAEFR is a safe and minimally invasive treatment for patients with gastric SMT, and could be a more reasonable and economical alternative to other laparoscopic procedures.


Submucosal tumor SMT Endoscopic submucosal dissection ESD Endoscopic full-thickness resection Natural orifice translumenal endoscopic surgery NOTES 


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Nobutsugu Abe
    • 1
    Email author
  • Hirohisa Takeuchi
    • 1
  • Osamu Yanagida
    • 1
  • Tadahiko Masaki
    • 1
  • Toshiyuki Mori
    • 1
  • Masanori Sugiyama
    • 1
  • Yutaka Atomi
    • 1
  1. 1.Department of SurgeryKyorin University School of MedicineTokyoJapan

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