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Surgical Endoscopy

, Volume 23, Issue 8, pp 1901–1907 | Cite as

A new electrocautery pleural biopsy technique using an insulated-tip diathermic knife during semirigid pleuroscopy

  • Shinji SasadaEmail author
  • Kunimitsu Kawahara
  • Yoko Kusunoki
  • Norio Okamoto
  • Teruo Iwasaki
  • Hidekazu Suzuki
  • Masashi Kobayashi
  • Tomonori Hirashima
  • Kaoru Matsui
  • Mitsunori Ohta
  • Teruomi Miyazawa
New Technology

Abstract

Background

The biopsy size obtained with standard flexible forceps (SFF) during semirigid pleuroscopy is often insufficient for pathological examination. An insulated-tip diathermic knife (IT knife) allows safe resection of a larger lesion during gastrointestinal endoscopy. We sought to validate an electrocautery pleural biopsy technique using the IT knife during semirigid pleuroscopy. We compared the diagnosis of specimens obtained using the IT knife and SFF in 20 subjects with unexplained pleural effusion, and reviewed pleuroscopic parameters such as complications, procedure time, and diameter of the specimens.

Methods

After injecting saline with lidocaine and epinephrine below the affected pleura, the lesion was incised in a circular shape with full thickness by manipulating the IT knife.

Results

Diagnostic yields from specimens obtained with the IT knife and SFF were 85% (17 of 20 cases) and 60% (12 of 20 cases), respectively. The IT knife biopsy was superior to SFF in 8 of 20 patients (malignant pleural mesothelioma in three, nonspecific inflammation in two, metastatic breast cancer in one, and tuberculosis in one). These pleural lesions revealed thickened, smooth abnormal appearances. The overall diagnostic yield for both IT knife and SFF was 100%. Median time of the procedure, from first pleural injection to specimen removal, was 21 min (range 12–92 min), and median diameter of specimen was 13 mm (range 6–23 mm). There were no severe complications during the procedure.

Conclusions

Electrocautery biopsy using the IT knife during semirigid pleuroscopy has great potential for diagnosing smooth abnormal pleura which are difficult to biopsy with SFF.

Keywords

Insulated-tip diathermic knife Electrocautery pleural biopsy Semirigid pleuroscope Smooth abnormal pleura Full-thickness pleura 

Abbreviations

IT knife

Insulated-tip diathermic knife

SFF

Standard flexible forceps

ESD

Endoscopic submucosal dissection

MPM

Malignant pleural mesothelioma

DDM

Desmoplastic malignant mesothelioma

Notes

Acknowledgements

The authors would like to thank the many nurses and physicians who participated in the care of patients in the study; Dr. Tomoki Michida for providing technical advice on using the IT knife; Dr. Atsuko Ishida for supporting the study; and Dr. Teruaki Nagano for supporting the pathologic examinations. This work was supported by grants from the Osaka Medical Research Foundation for Incurable Diseases.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Shinji Sasada
    • 1
    Email author
  • Kunimitsu Kawahara
    • 2
  • Yoko Kusunoki
    • 1
  • Norio Okamoto
    • 1
  • Teruo Iwasaki
    • 3
  • Hidekazu Suzuki
    • 1
  • Masashi Kobayashi
    • 1
  • Tomonori Hirashima
    • 1
  • Kaoru Matsui
    • 1
  • Mitsunori Ohta
    • 3
  • Teruomi Miyazawa
    • 4
  1. 1.Department of Thoracic MalignancyOsaka Prefectural Medical Center for Respiratory and Allergic Diseases OsakaJapan
  2. 2.Department of PathologyOsaka Prefectural Medical Center for Respiratory and Allergic DiseasesOsaka Japan
  3. 3.Department of Pulmonary SurgeryOsaka Prefectural Medical Center for Respiratory and Allergic DiseasesOsaka Japan
  4. 4.Department of Pulmonology St. Marianna University School of Medicine KanagawaJapan

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