Surgical Endoscopy

, Volume 21, Issue 11, pp 1985–1990 | Cite as

Nissen versus Toupet fundoplication: Results of a randomized and multicenter trial

  • E. Guérin
  • K. Bétroune
  • J. Closset
  • A. Mehdi
  • J. C. Lefèbvre
  • J. J. Houben
  • M. Gelin
  • P. Vaneukem
  • I. El Nakadi
Article

Abstract

Background

Laparoscopic Toupet fundoplication (TF) is reported to be as effective as Nissen (NF), but to be associated with fewer unfavorable postoperative side-effects. This study evaluates the one- and three-year clinical outcome of 140 randomized patients after a laparoscopic NF or TF.

Patients and methods

Inclusion criteria included patients over 16 years old with complications of gastro-oesophageal reflux disease (GORD) and persistence or recurrence of symptoms after three months of treatment. Subjects with a previous history of gastric surgery or repeated fundoplication, brachy-oesophagus or severe abnormal manometry results were excluded. Seventy-seven NF and 63 TF were performed. The severity of symptoms was assessed before and after the procedure.

Results

One hundred and twenty-one of the 140 patients after one year, and 118 after three years, were evaluated and no statistically significant clinical difference was observed. The level of satisfaction concerning the outcome of the operation remained high after one or three years regardless of the type of fundoplication performed.

Conclusions

Functional complications after NF are not avoided with TF.

Keywords

Gastro-oesophageal reflux disease (GORD) Laparoscopic Nissen fundoplication Laparoscopic Toupet fundoplication 

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • E. Guérin
    • 1
  • K. Bétroune
    • 2
  • J. Closset
    • 2
  • A. Mehdi
    • 3
  • J. C. Lefèbvre
    • 1
  • J. J. Houben
    • 2
  • M. Gelin
    • 2
  • P. Vaneukem
    • 1
  • I. El Nakadi
    • 2
  1. 1.Department of Digestive SurgeryCentre Hospitalier Universitaire (CHU) de CharleroiCharleroiBelgium
  2. 2.Department of Digestive SurgeryErasme HospitalBrusselsBelgium
  3. 3.Department of Digestive SurgeryCentre Hospitalier Etterbeek Ixelles (CHEI)-HISBrusselsBelgium

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