Surgical Endoscopy

, Volume 21, Issue 5, pp 747–753

Randomized trial of health-related quality of life after open and laparoscopic surgery for colon cancer

  • Martin Janson
  • Elisabet Lindholm
  • Bo Anderberg
  • Eva Haglind



Randomized controlled trials (RCTs) have reported improved or unchanged three-year survival following laparoscopic colon resection (LCR) for colon cancer compared with that following open resection (OCR). The aim of this study was to determine health-related quality of life (HRQL) in patients randomized to laparoscopic or open resection for colon cancer.


In total, 285 patients (130 LCR, 155 OCR) from seven Swedish centers were included. HRQL was assessed preoperatively and at 2, 4, and 12 weeks postoperatively with the EQ-5D and EORTC QLQ-C30 instruments.


The LCR patients did significantly better on the social function component of the EORTC QLQ-C30 at two and four weeks and on the role function component at two weeks.


Laparoscopic resection for colon cancer improved quality of life during the first postoperative month.


Laparoscopy Colonic neoplasms Quality of life Randomized controlled trial 

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Martin Janson
    • 1
  • Elisabet Lindholm
    • 2
  • Bo Anderberg
    • 3
  • Eva Haglind
    • 2
  1. 1.Department of SurgeryKarolinska Institutet at Karolinska University Hospital HuddingeStockholmSweden
  2. 2.Department of SurgeryInstitute of Surgical Sciences, Göteborg University, Sahlgrenska University HospitalGöteborgSweden
  3. 3.Department of Molecular Medicine and SurgeryKarolinska Institutet at Karolinska University Hospital SolnaStockholmSweden

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