Metaanalysis of trials comparing laparoscopic and open surgery for Crohn’s disease

Article
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Abstract

Background:

Several studies in the literature have suggested that laparoscopic surgery for Crohn’s disease is associated with faster postoperative recovery and a morbidity and recurrence rate similar to that for open surgery. Most of these studies have been limited by a small sample size and a short follow-up period.

Methods:

To clarify whether open or laparoscopic resection results in a better outcome, a metaanalysis of studies was performed comparing the two procedures for Crohn’s disease. Pooled effects were estimated using a random-effects model.

Results:

Laparoscopic surgery required more operative time than open surgery (26.8 min; 95% confidence interval [CI], 6.4–47.2 min), but resulted in a shorter duration of ileus and a decreased hospital stay (−2.62 days; 95% CI, −3.62 to −1.62). Laparoscopic surgery also was associated with a decreased rate for postoperative bowel obstruction and surgical recurrences.

Conclusions:

Laparoscopic surgery for Crohn’s disease is feasible, safe, and associated with shorter duration of ileus and a shorter hospital stay.

Keywords

Crohn’s disease Laparoscopic surgery Metaanalysis 
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Notes

Acknowledgments

The authors thank Drs. Mark Korsten and Randolph Steinhagen for their clinical expertise.

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  1. 1.Section of Gastroenterology and Medicine ProgramBronx VAMC and Mount Sinai School of MedicineNew YorkUSA
  2. 2.Department of SurgeryUniversity of ChicagoChicagoUSA

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