Surgical Endoscopy And Other Interventional Techniques

, Volume 19, Issue 9, pp 1172–1176

Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer

Original Article



Laparoscopy-assisted surgery with extraperigastric lymph node dissection for gastric cancers has been described, but the clinical benefits of these surgeries still are unclear. Short-term clinical outcomes were compared between laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for early gastric cancer in a prospective randomized fashion.


For this study, 28 patients with early gastric cancers in the lower half of the stomach were randomly assigned to either LADG (n = 4) or ODG (n = 14). Postoperative pain, levels of acute inflammatory responses, and pathologic evaluation of the operative specimens were compared.


The LADG group required a significantly shorter period of postoperative epidural anesthesia, showed significantly lower levels of serum interleukin-6 and C-reactive protein, and had no major postsurgery complications. Pathologic examinations showed that surgery was equally radical in the two groups.


The findings show that LADG with extraperigastric lymph node dissection is a safe and less invasive alternative to the open procedure.

Key words:

Gastric cancer Distal gastrectomy Extended lymphadenectomy Laparoscopy Randomized control trial Billroth I reconstruction 


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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  1. 1.Research Center for Frontier Medical EngineeringInage-kuJapan
  2. 2.Department of Academic SurgeryGraduate School of Medicine, Chiba UniversityJapan

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