Dysphagia

, Volume 28, Issue 2, pp 217–225 | Cite as

Changes in Tongue Pressure, Pulmonary Function, and Salivary Flow in Patients with Amyotrophic Lateral Sclerosis

  • Caryn Easterling
  • Jodi Antinoja
  • Susan Cashin
  • Paul E. Barkhaus
Original Paper

Abstract

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease involving nerve cells that control voluntary muscle movement (Rowland LP, Shneider NA, N Engl J Med 344(22):1688–1700, 2001). The aim of this study were to determine the pattern of neurodegenerative change in (1) isometric tongue strength (ITS) and spontaneous saliva swallow (SSS) pressure, (2) saliva weight, and (3) forced vital capacity (FVC) in patients with ALS who present with primary spinal versus primary bulbar symptoms. Twenty-three consecutive patients (age = 48–80 years, mean = 59.5 years) were enrolled. Data were collected over three visits (12-week interval) for each group: 9 patients with bulbar symptoms and 14 with spinal symptoms. A significant difference was noted in SSS and ITS in the group with bulbar symptoms from Trial 1 to II and from Trial II to III. SSS and ITS showed a significant difference when comparing Trial I to III but not when comparing Trial I to II for the spinal symptom group, indicating that this group experienced a slower decline in SSS. Saliva production did not show a significant change in the bulbar symptom group but did in the spinal group. FVC was significantly different when comparing Trial I to III and Trial II to III for both groups. FVC, SSS, and ITS may be complimentary measures used as a gauge of an ALS patient’s ability to efficiently take oral nutrition and to support required alterations in diet consistency.

Keywords

Deglutition Deglutition disorders Amyotrophic lateral sclerosis Tongue strength Saliva Respiration 

Notes

Conflict of interest

The authors have no conflicts of interest to disclose.

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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Caryn Easterling
    • 1
    • 3
  • Jodi Antinoja
    • 2
  • Susan Cashin
    • 4
  • Paul E. Barkhaus
    • 3
  1. 1.Department of Communication Sciences and Disorders, College of Health SciencesUniversity of Wisconsin-MilwaukeeMilwaukeeUSA
  2. 2.Department of Speech Language PathologyFroedtert HospitalMilwaukeeUSA
  3. 3.Department of NeurologyMedical College of WisconsinMilwaukeeUSA
  4. 4.College of Health SciencesUniversity of Wisconsin-MilwaukeeMilwaukeeUSA

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